Kellogg J. Schwab, PhD
Center & Institute Affiliations
- Bill and Melinda Gates Institute for Population and Reproductive Health
- Center for Global Health
- Center for Human Nutrition
- Johns Hopkins University Global mHealth Initiative (JHU-GmI)
- Risk Sciences and Public Policy Institute
- The Johns Hopkins University Water Institute
615 N. Wolfe Street
Baltimore, Maryland 21205
PhD, University of North Carolina, Chapel Hill, 1995
MSPH, University of North Carolina, Chapel Hill, 1991
Kellogg Schwab is a Professor in the Department of Environmental Health Sciences at the Johns Hopkins University Bloomberg School of Public Health and Director of the JHU Water Institute.
The JHU Water Institute integrates Hopkins researchers from across the university including public health, engineering, arts and sciences, business, behavior, policy and economic disciplines to address the critical triangle of water, food and energy. The goal of this Institute is to achieve sustainable, scalable solutions for disparate water and sanitation needs both internationally and domestically.
Dr. Schwab’s research focuses on environmental microbiology and engineering with an emphasis on the fate and transport of pathogenic microorganisms in water, food and the environment. This work includes extensive laboratory-based research designed to develop and evaluate molecular detection methods with subsequent application of these methods in field-based investigations. Data gathered during these studies are then integrated into exposure assessments for risk analysis and microbial risk assessment.
In collaboration with the Centers for Disease Control and Prevention and state health laboratories Dr. Schwab has investigated numerous waterborne and foodborne outbreaks of viral gastroenteritis. Dr. Schwab’s current research projects involve improving environmental detection methods for noroviruses (the leading cause of non-bacterial gastroenteritis worldwide) by integrating quantitative reverse transcription-PCR, proteomics and pyrosequencing. He is also investigating how important human pathogens including noroviruses, hepatitis A virus, rotaviruses, Campylobacter, antibiotic resistant E. coli and enterococci, Cryptosporidium parvum, Toxoplasma gondii and molds such as Aspergillus persist and are transported through environmental media (water, air, and food).
Applying classical and molecular diagnostic tools, he has developed and participated in multiple research projects designed to evaluate the public health impacts of improving water access and potable water quality and the effectiveness of point-of-use water treatment. His research group has also examined the health effects of inadequate management of human and animal waste with a focus on assessing the impact of concentrated animal feeding operations on human health, the environment and quality of life in the communities in which these operations are located. He continues to evaluate the impact of human pollution on urban streams and the Chesapeake Bay caused by aging and deteriorating distribution systems by combining microbial, chemical and geographic information system (GIS) data.
Recent international work has focused on developing field-portable microbial and chemical laboratories. These self-contained labs facilitate evidence-based assessments of point of use and community level water treatment systems designed to provide potable water to individuals in low income countries including Nicaragua, Peru, Ghana and South Africa.
Honors and Awards
Graduate Student Travel Award, 1993 Hoechst Celanese Excellence in Graduate Research Award, 1993 American Society of Microbiology Travel Award, 1995 Division of Molecular Virology Training Award, 1997-1999 Division of Molecular Virology Award for Excellence in Postdoctoral Research, 1999 Johns Hopkins Award for Excellence in Advising, Mentoring and Teaching, 2005 Delta Omega Public Health Honor Society Alpha Chapter 2009, American Society for Microbiology Distinguished Lecturer 2012-14, Fellow of the American Academy of Microbiology 2015
- Environmental Health Sciences, environmental microbiology, microbial fate and transport, water quality, drinking water treatment, disinfection, groundwater, wastewater, sewage, water and wastewater distribution systems, gastroenteritis, diarrhea, enteric pathogens, parasites (cryptosporidium, toxoplasma, giardia), viruses (norovirus, norwalk-like viruses, hepatitis A virus, rotavirus), bacterial indicators of water quality, bacteriophage, antibiotic resistant bacteria, molecular detection of microorganisms (PCR, RT-PCR, microarrays, hybridization), infectious diseases, microbial risk assessment, food borne and waterborne outbreak investigations, urban environmental pollution, airborne microorganisms, concentrated animal feeding operations (CAFO), Chesapeake Bay research
Select recent publications from five areas of research
Weng SC, Luo Y, Li J, Zhou B, Jacangelo JG, Schwab KJ. Assessment and Speciation of Chlorine Demand in Fresh-Cut Produce Wash Water. In press. Food Research. 2015.
Huang H, Fairbrother H, Teychene B, Ajmani G, Abbott Chalew TE, Cho, HH, Schwab KJ, Janangelo J. Carbon nanotube composite membranes for small “designer” waer treatment systems. Water Science and Technology: Water Supply. V145. pp917-923. 2014.
Julian TR, Trumble JM, Schwab KJ. Evaluating efficacy of field-generated electrochemical oxidants on disinfection of fomites using bacteriophage MS2 and mouse norovirus MNV-1 as pathogenic virus surrogates. Food and Environmental Virology. DOI 10.1007/s12560-014-9136-6. 2014.
Huang H, Cho H, Jacangelo J, Schwab KJ. Mechanisms of membrane fouling control by integrated magnetic ion exchange and coagulation. Env. Sci Technol. V46, p10711-10717. 2012.
Ajmani G, Goodwin D, Marsh K, Fairbrother DH, Schwab KJ, Janangelo J, Huang H, Modification of low pressure membranes with carbon nanotube layers for fouling control. Water Research, V46(17) pp5645-5654. 2012.
Huang H, Cho H, Schwab KJ. Jacangelo JG, Effects of magnetic ion exchange pretreatment on low pressure membrane filtration of natural surface water. Water Research, V46(17) pp5483-5490. 2012.
Fate and Transport of Nanoparticles in the Environment
Ajmani G, Cho, HH, Abbott Chalew TE, Schwab KJ, Janangelo J, Huang H, Static and dynamic removal of aquatic natural organic matter by carbon nanotubes. Water Research. V59. pp 262-270. 2014.
Chalew T, Ajmani G, Huang H, Schwab KJ. Evaluating nanoparticle breakthrough during drinking water treatment: a pathway of human exposure. Env. Health Perspectives. V121(10). pp 1161-1166. 2013.
Chalew T, Schwab KJ. Toxicity of commercially available engineered nanoparticles to Caco-2 and SW 480 human intestinal epithelial cells. Cell Biol. Toxicol. V29(2). pp 101-116. 2013.
Julian TR, Baugher JD, Rippinger C, Pinekenstein R, Kolawole AO, Mehoke T, Wobus CE, Feldman A, Pineda FJ, Schwab KJ. Murine norovirus (MNV-1) exposure in vitro to the purine nucleoside analog Ribavirin increases quasispecies diversity. Accepted for publication. Virus Research. 2015.
Hartmann E, Colquhoun D, Schwab KJ, Halden R. Absolute Quantification of Norovirus Capsid Protein in Food, Water, and Soil Using Synthetic Peptides with Electrospray and MALDI Mass Spectrometry. J of Hazardous Materials. V286. pp 525–532. 2015.
Gibson KE, Schwab KJ, Spencer BS, Borchardt M. Measuring and Mitigating Inhibition during Quantitative Real Time PCR Analysis of Viral Nucleic Acid Extracts from Large-Volume Environmental Water Samples. Water Research, V46 pp4281-4291. 2012
Julian T, Schwab KJ. Challenges in environmental detection of human viral pathogens. Current Opinion in Virology. V2 p 1-6. 2012
Seitz SR, Leon JS, Schwab KJ, Marshall Lyon G, Dowd M, McDaniels M, Abdulhafid G, Fernandez ML, Lindesmith L, Baric R, Moe CL. Norovirus infectivity in humans and persistence in water. Appl. Environ. Microbiol.V77 (19), p 6884-6888. 2011.
Gibson KE, Schwab KJ. Thermal inactivation of human norovirus surrogates. Food and Environ Virology. V3 (2) p 74-77. 2011.
Gibson KE, Schwab KJ. Detection of Bacterial Indicators and Human and Bovine Enteric Viruses in 100 L Surface and Ground Water Samples Potentially Impacted by Animal and Human Wastes in Lower Yakima Valley, Washington. Appl. Environ. Microbiol. 77 (1), p355-362. 2011.
Gibson KE, Schwab KJ. Tangential Flow Ultrafiltration with Integrated Inhibition Detection for the Recovery of Surrogates and Human Pathogens from Large-Volume Source and Finished Drinking Water. Appl. Environ. Microbiol. 77 (1), p385-391. 2011.
Fuhrmeister E, Schwab KJ, Julian T. Estimates of Nitrogen, Phosphorus, Biochemical Oxygen Demand, and Fecal Coliform Entering the Environment Due to Inadequate Sanitation Treatment Technologies in 108 Low and Middle Income Countries. In Press. Envir Sci Technology. 2015.
Ntozini R, Marks SJ, Mangwadu G, Mbuya M, Gerema G, Mutasa B, Julian TR, Schwab KJ, Humphrey JH, Zungu LI, and The Shine Team. Assessing household water access and sanitation coverage using geographic information systems and spatial analysis within the SHINE Trial study in rural Zimbabwe. Accepted for Publication. Clinical Infectious Diseases. 2015.
Julian T, Islam MA, Pickering A, Roy S, Fuhrmeister E, Ercumen A, Harris A, Bishai J, Schwab KJ. Genotypic and phenotypic characterization of Escherichia coli isolated from feces, hands, and soils in rural Bangladesh using the Colilert Quanti-Tray System (IDEXX). Appl. Env. Micro. V81 pp 1735-1743. 2015.
Opryszko M, Guo Y, MacDonald L, MacDonald L, Kiihl S, Schwab KJ. Impact of water-vending kiosks and hygiene education on household drinking water quality in rural Ghana. American J. Tropical Medicine and Hygiene, V88(4) pp 651-660. 2013.
Julian T, MacDonald L, Guo Y, Marks S, Kosek M, Yori P, Pinedo S, Schwab KJ. Fecal Indicator Bacteria Contamination of Fomites and Household Demand for Surface Disinfection Products – A Case Study from Peru. American J. Tropical Medicine and Hygiene. V89(5). Pp869-872. 2013.
Pickering A, Julian T, Marks S, Mattioli M, Boehm A, Schwab KJ, Davis, J. Fecal contamination and diarrheal pathogens on surfaces and in soils among Tanzanian households with and without improved sanitation. Environ. Sci. and Technol.V46 (11), p5736-43. 2012.
Harding A, Schwab KJ. Using limes and synthetic psoralens to enhance solar disinfection of water (SODIS): A laboratory evaluation with norovirus, Escherichia coli, and MS2. Am. J. Trop. Med. Hyg. V86 (4). P566-572. 2012.
Alcorn T, Opryszko M, Schwab KJ. Formative ethnographic research to improve the evaluation of a novel water system in Ghana. American J. Tropical Medicine and Hygiene. V84 (5) p.801-805. 2011.
Gibson KE, Opryszko M, Schissler J, Guo Y, Schwab KJ. Evaluation of Human Enteric Viruses in Surface Water and Drinking Water Resources in Southern Ghana. American J. Tropical Medicine and Hygiene. 84(1). p20-29. 2011.
Environmental Exposure including Antibiotic Resistance
Haack SK, Duris JW, Kolpin DW, Fogarty LR, Johnson HE, Gibson KE, Focazio M, Schwab KJ, Hubbard LE, Foreman WT Genes indicating zoonotic and swine pathogens are persistent in stream water and sediment following a swine manure spill. Applied Environmental Microbiology, V81. pp 3430-3441. 2015.
Soller J, Eftim S, Wade TJ, Ichida A, Clancy J, Johnson T, Schwab KJ, Ramirez-Toro G, Nappier S, Ravenscroft J. Use of quantitative microbial risk assessment to improve interpretation of a recreational water epidemiological study. doi:10.1016/j.mran.2015.04.001 In press, Microbial Risk Analysis. 2015.
Heaney CD, Exum NG, Dufour AP, Brenner KP, Haugland RA, Chern E, Schwab KJ, Love DC, Serre ML, Noble R, Wade TJ. Water quality, weather and environmental factors associated with fecal indicator organism density in beach sand at two recreational marine beaches. Science of the Total Environment. V497-498. pp440-447. 2014.
Sapkota AR, Kinney EL, George A, Hulet RM, Cruz-Cano R, McDermott P, Schwab KJ, Zhang G, Joseph SW. Lower Prevalence of Antibiotic-resistant Salmonella on Large-Scale U.S. Conventional Poultry Farms that Transitioned to Organic Practices. Science of the Total Environment. V476-477. pp387-392. 2014.
Sapkota AR, Hulet RM, Zhang G, McDermott P, Schwab KJ, Joseph SW. Immediate reductions in the prevalence of antibiotic-resistant Enterococci as U.S. conventional poultry farms transition to organic practices. Environ Health Perspect. V119 (11). p1622-1628, 2011.
- An Assessment of Water Quality in Lima’s Peri-Urban Neighborhoods
- Chemical and Microbial Assessment of Sewage Spills
- Efficiency of Secondary Sewage Treatment Systems
- Identification and Enumeration of Pathogens in Drinking Water
- MWH-Global JHU Alliance
- Performance Monitoring and Accountability 2020 (PMA2020)
- Point-of-Use Evaluation
- Ram Pump Irrigation in KwaZulu-Natal
- Ultrahigh-throughput virus-host cell picoreactor system for predictive modeling of viral evolution.