Jonathan E. Golub, PhD
Center & Institute Affiliation(s):
1550 Orleans St., Suite 1M.07
Baltimore , Maryland 21231
My primary research focus is the epidemiology of tuberculosis, primarily in the context of HIV infection. I currently lead a large community randomized trial in Brazil investigating isoniazid preventive therapy for HIV-infected patients as part of the Bill and Melinda Gates Foundation funded CREATE consortium. I also conduct research in South Africa, working on several HIV-related studies at the Chris Hani Baragwanath Hospital in Soweto. A strong interest is the association between smoking and TB and smoking and HIV. I am conducting studies in South Korea, Brazil, South Africa, Pakistan and the Republic of Georgia on smoking and TB, and recently began a smoking cessation trial in South Africa for HIV-infected patients. Another area of interest is diabetes and TB and we will soon be starting an NIH sponsored prospective cohort study investigating differences in TB outcomes between TB patients with and without TB.
Since 2005, I have been the primary instructor for the Epidemiologic Basis for Tuberculosis Control, a class developed by Dr. George W. Comstock. This course is conducted twice-yearly, both in class and online as part of the distance education program at Johns Hopkins University. I have also developed a one-year training course for Brazilian and South African clinicians and epidemiologists emphasizing methods in developing, implementing and analyzing epidemiologic studies. This course concentrates on HIV/TB population research, and has now expanded through another training grant to include trainees from these countries interested in HIV-related malignancies.
Golub JE, Astemborski J, Ahmed M, Cronin W, Mehta SH, Kirk GD, Vlahov D, Chaisson RE. Long-term effectiveness of diagnosing and treating latent tuberculosis infection in a cohort of HIV-infected and at risk injection drug users. JAIDS 2008; In Press.
Cailleaux-Cezar M, Melo DA, Xavier GM, Salles CLG, Mello FCQ, Ruffino-Netto A, Golub JE, Efron A, Chaisson RE, Conde MB. Incidence of Tuberculosis Among Contacts of Active Pulmonary Tuberculosis. International Journal of Tuberculosis and Lung Disease 2008; In Press.
Pacheco AG, Durovni B, Cavalcante SC, Lauria LM, Moore RD, Moulton LH, Chaisson RE, Golub JE. AIDS-related tuberculosis in Rio de Janeiro, Brazil. PLoS ONE 2008; 3(9):e3132.
Pacheco AG, Saraceni V, Tubor SH, Moulton SH, Chaisson RE, Cavalcante SC, Durovni B, Faulhaber JC, Golub JE, King B, Schechter M, Harrison LH. Validation of a hierarchical deterministic record linkage algorithm using data from two different cohorts of HIV-infected individuals and mortality databases in Brazil. American Journal of Epidemiology 2008;168(11):1326-32
Golub JE, Durovni B, King BS, Cavalcante SC, Pacheco AG, Moulton LH, Moore RD, Chaisson RE, Saraceni V. Recurrent tuberculosis in HIV-infected patients in Rio de Janeiro, Brazil. AIDS 2008;22(18): 2527-2533.