Integrated Health Sciences Facility Core (IHSFC)
The IHSFC of the Center facilitates and enhances the speed at which translation of basic research discovery occurs into clinical or public health applications by members of the Johns Hopkins NIEHS Center in Urban Environmental Health.
The specific objectives of this core are:
- To provide services and access to instrumentation and technologies that foster integration of basic science into public health research, including epidemiology, prevention and intervention studies.
- To support research to improve exposure characterization, early detection of disease risk, biomarker discovery and development of preventive interventions for environmentally related diseases.
- To enhance partnerships between researchers and the community that impact on conduct of clinical and public health research through the linkage of the IHSFC with the Community Outreach and Education Core (COEC) in this Center.
Bio-Informatics and Statistics Core (BISC)
Environmental health research relies on the integration of molecular, clinical and population sciences. It is increasingly dependent on the acquisition, management and use of complex information. Hence, statistical and informatics methods are essential for success. Today, Center scientists routinely rely on bioinformatics, biostatistics, mathematics, and computing tools to design, implement, and analyze data from their experiments and observational studies. BISC introduces Center members to the optimal tools when they exist and create new ones when they do not. Center members are benefited when their research program is made more productive through their consultations and collaborations with BISC faculty. They produce more knowledge from the same investment of resources when they use optimal quantitative methods.
BISC methods research also benefits Center investigators indirectly. When our novel methods such as spatial time series models or gene expression measures are adopted by the larger research community, progress is more rapid and Center members benefit from the discoveries of others that are facilitated by BISC generated tools.