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Course Catalog

223.665.81 Infection, Immunity and Undernutrition: Interactions and Effects

International Health
3rd term
4 credits
Academic Year:
2013 - 2014
Auditors Allowed:
Grading Restriction:
Letter Grade or Pass/Fail
Christian Coles
Course Instructor:

Introduction to Online Learning. A basic knowledge of immunology and nutrition is desirable.


Reviews current data on the metabolic, physiologic and endocrinological events that comprise, the acute phase responses of the body to infection. Discusses the detrimental impact of these, responses on nutrient intake, metabolism, absorptions, and losses. Examines the deleterious effects of undernutrition and micronutrient deficiencies on host barrier defenses, innate,, mucosal, humoral and cell-mediated immunity, and pathogen virulence. Evaluates the influence of nutritional status on responses to vaccination and antimicrobial therapy.

Learning Objectives:

Upon successfully completing this course, students will be able to:

  1. describe the impact of infectious diseases on nutritional status
  2. explain the general effects of undernutrition and micronutrient deficiencies on host immunity and the impact on immunity to the major infectious causes of child morbidity and mortality
  3. Discuss the implications for the control of pediatric infectious diseases in low income countries
Methods of Assessment:

Web-based quizzes on course readings (10%), web-based student presentations through live
talk sessions (50%) and web-based final examination (40%)

Instructor Consent:

No consent required