Guy McKhann
Professor of Neurology and Neuroscience

Academic Degrees
M.D., Yale University School of Medicine, 1955.

Departmental Affiliation
Dept. of Neurology

Departmental Address
338 Krieger Hall
3400 N. Charles St.
Baltimore, MD  21218-2685

Email: guy.mckhann@jhu.edu
Phone: (410)-516-8640
Fax:

Honors and Awards

• Alpha Omega Alpha, 1954
• Joseph D. Kennedy, Jr. Foundation Sr. Research Scholar, 1963
• John and Mary R. Markle Scholar in Academic Medicine, 1964
• Medical Student Teaching Award, Johns Hopkins, 1974
• Weinstein-Goldenson Research Award from United Cerebral Palsy, 1978
• Macy Faculty Ward, 1982
• Member, Institute of Medicine, National Academy of Sciences, 1991
• Fellow, American Association for the Advancement of Science, 1994
• M.D. (Honorary) Hebei Medical College, Shijiazhuang, P.R.C. 1994
• Johns Hopkins Undergraduate Teaching Award, 1996
• Fellow, The Royal College of Physicians, 2002
• Honorary Member, American Neurological Association, 2003

Selected Publications

Fine RL, Chen J, Balmaceda C, Bruce JN, Huang M, Desai M, Sisti MB, McKhann GM, Goodman RR, Bertino JS Jr, Nafziger AN, Fetell MR. Randomized study of paclitaxel and tamoxifen deposition into human brain tumors: implications for the treatment of metastatic brain tumors. Clin Cancer Res. 2006 Oct 1;12(19):5770-6.    

Gottesman RF, Sherman PM, Grega MA, Yousem DM, Borowicz LM Jr, Selnes OA, Baumgartner WA, McKhann GM. Watershed strokes after cardiac surgery: diagnosis, etiology, and outcome. Stroke. 2006 Sep;37(9):2306-11. Epub 2006 Jul 20.    

Selnes OA, McKhann GM, Borowicz LM Jr, Grega MA. Cognitive and neurobehavioral dysfunction after cardiac bypass procedures. Neurol Clin. 2006 Feb;24(1):133-45. Review.  

Chen J, Balmaceda C, Bruce JN, Sisti MB, Huang M, Cheung YK, McKhann GM, Goodman RR, Fine RL. Tamoxifen paradoxically decreases paclitaxel deposition into cerebrospinal fluid of brain tumor patients. J Neurooncol. 2006 Jan;76(1):85-92.  

McKhann GM, Grega MA, Borowicz LM Jr, Baumgartner WA, Selnes OA. Stroke and encephalopathy after cardiac surgery: an update. Stroke. 2006 Feb;37(2):562-71. Epub 2005 Dec 22. Review.  

McKhann GM, Grega MA, Borowicz LM Jr, Bailey MM, Barry SJ, Zeger SL, Baumgartner WA, Selnes OA. Is there cognitive decline 1 year after CABG? Comparison with surgical and nonsurgical controls. Neurology. 2005 Oct 11;65(7):991-9. Epub 2005 Aug 17.  

Selnes OA, McKhann GM. Neurocognitive complications after coronary artery bypass surgery. Ann Neurol. 2005 May;57(5):615-21. Review.  

Selnes OA, Grega MA, Borowicz LM Jr, Barry S, Zeger S, Baumgartner WA, McKhann GM.  Cognitive outcomes three years after coronary artery bypass surgery: a comparison of on-pump coronary artery bypass graft surgery and nonsurgical controls. Ann Thorac Surg. 2005 Apr;79(4):1201-9.  

Barry SJ, Zeger SL, Selnes OA, Grega MA, Borowicz LM Jr, McKhann GM. Quantitative methods for tracking cognitive change 3 years after coronary artery bypass surgery. Ann Thorac Surg. 2005 Apr;79(4):1104-9.  

Tamargo RJ, Connolly ES Jr, McKhann GM, Khandji A, Chang Y, Libien J, Adams D. Clinicopathological review: primary angiitis of the central nervous system in association with cerebral amyloid angiopathy. Neurosurgery. 2003 Jul;53(1):136-43; discussion 143.    

Magira EE, Papaioakim M, Nachamkin I, Asbury AK, Li CY, Ho TW, Griffin JW, McKhann GM, Monos DS. Differential distribution of HLA-DQ beta/DR beta epitopes in the two forms of Guillain-Barre syndrome, acute motor axonal neuropathy and acute inflammatory demyelinating polyneuropathy (AIDP): identification of DQ beta epitopes associated with susceptibility to and protection from AIDP. J Immunol. 2003 Mar 15;170(6):3074-80.  

Restrepo L, Wityk RJ, Grega MA, Borowicz L Jr, Barker PB, Jacobs MA,Beauchamp NJ, Hillis AE, McKhann GM. Diffusion- and perfusion-weighted magnetic resonance imaging of the brain before and after coronary artery bypass grafting surgery. Stroke. 2002 Dec;33(12):2909-15.     

Selnes OA, Grega MA, Borowicz LM Jr.,Barry S, Zeger S, McKhann GM. Self-reported memory symptoms with coronary artery disease: a prospective study of CABG patients and nonsurgical controls. Archives of Neurology (2004).

Selnes OA, Grega MA, Borowicz LM, Royall RM, McKhann GM, and Baumgartner WA: Cognitive Changes with coronary artery disease: a prospective study of CABG patients and nonsurgical controls. Annals of Thoracic Surgery. 75:1377-1386, 2003.

McKhann GM, Grega MA, Borowicz LM, Bechamps M, Selnes OA, Baumgartner WA, and Royall RM: Encephalopathy and Stroke After Coronary Artery Bypass Grafting: Incidence, Consequences, and Prediction. Arch Neurol 59:1422-1428, 2002.

Borowicz LM, Selnes OA, Goldsborough MA, Royall RM, Lyketsos CG, Quaskey SA, and McKhann GM: Depression and cardiac morbidity 5 yers after coronary artery bypass surgery. Psychosom 33:2909-2915, 2002.