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Gary Wand
Professor of Medicine and Psychiatry

Academic Degrees
M.D., George Washington University Medical School, 1980

Departmental Affiliation
Dept of Medicine – Endocrinology

Departmental Address
863 Ross – Endocrinology
600 North Wolfe Street
Baltimore, MD 21287

Phone: (410)-955-7225
Fax: (410)-955-0841

Honors and Awards:

Summa Cum Laude; Periclean Honor Society; Phi Beta Kappa, 1975
hysician Scientist Award; 1984-89
Clinician Scientist Award; 1987-89
First Award, National Institutes of Health; 1988-93
American College of Physicians Research Scholar; 1990-93
Listed in "Best Doctors in America”
The National Institutes of Health Merit Award

Selected Publications

     Wand, G.S., McCaul M, Reynolds J, Gotjen, D., Ali A. (2002) The mu opioid receptor gene polymorphism A(118)G alters HPA axis activation induced by opioid receptor blockade. Neuropsychopharmacology 26:106-114.   

     Hernandez-Avila, C., Oncken C., Van Kirk J., Wand, G.S., Kranzler H. (2002) ACTH and cortisol responses to a naloxone challenge and risk for alcoholism. Journal of Biological Psychiatry 51:652-658.

     Yang X, Oswald L, Wand, G.S. (2003) Cylic AMP/PKA signal transduction pathway and tolerance to ethanol. Alcoholism Clin Exp Res 27:1220.

     Oswald L. and Wand, G.S. (2004) Comparison of HPA axis hormone responses to naloxone vs. psychologically-induced stress. Psychoneuroendocrinology 29:371-388.

     Szabo Z, Owonikoko, T, Peyrot M, Mathews WB, Ravert HT, Dannals RF, Wand, G.S.  (2004) Positron emission tomography imaging of the serotonin transporters in the limbic structures of subjects with history of alcoholism. Biol Psychiatry 55(7):766-71.

    Bencherif  B, Wand, G.S., McCaul ME,  Kim YK,  Dannals R,  Frost  J. (2004) Mu-Opioid Receptor Binding Measured by C-11 Carfentanil PET is Related to Craving in Human Alcohol Dependence. Biol Psychiatry. 2004 Feb 1; 55(3): 255-62.

    Salvatori, R., Yang, X., Wand, G.S. (2004) Novel Insertional Mutation in the Mu-Opioid Receptor Gene is Associated with Altered Sensitivity to Naloxone. Journal of Endocrine Genetics 3:129-134.

    Oswald L.M., Yang X, Wand, G.S. (2004) Association between ACTH and cortisol responses to opioid blockade and alleles of the catechol-O-methyltransferase (COMT) gene. Biol Psychiatry 1;55(1):102-5.

    Uhart M, McCaul M, Oswald L, Choi L, Wand, G.S. (2004) GABRA6 gene polymorphism is associated with an attenuated response to psychological stress. Molecular Psychiatry, 9(11):998-1006.

    Oswald LM, Wong DF, McCaul M, Zhou Y, Kuwabara H, Choi L, Brasic J, Wand, G.S. (2005)  Association of ventral striatal dopamine release with cortisol and drug liking. Neuropsychopharmacology, 30(4):821-32.

    Chong R, Oswald, L, Uhart M, Yang X, Ping L, Wand, G.S. (2006) The mu opioid receptor gene polymorphism A(118)G predicts cortisol responses to Naloxone and stress.  Neuropsychopharmacology, 31 (1):204-211.

    Munroe C, Oswald L, Weerts E, Zsabo S. Wand, G.S. (2005) Hormone responses to psychological  stress in alcohol dependent men and social drinkers. Alcohol Clin Exp Res. 29(7):1133-8.

    Munro C, McCaul M, Wong DF, Oswald L, Zhou Y, Kuwabara H, Choi L, Brasic J,  Wand, G.S. (2006) Sex differences in striatal dopamine release in healthy adults. Biol Psychiatry: 15;59(10):966-74.

    Munro C, McCaul M, Wong DF, Zhou Y, Kuwabara H, Choi L, Brasic J, Wand, G.S. (2006) Family history of alcoholism and striatal dopamine release. Alcoholism: Clinical and Experimental Research, Jul;30(7):1143-51.

    Uhart M, Chong R, Oswald, L, Ping L,  Wand, G.S. (2006) Gender differences in hypothalamic-pituitary-adrenal (HPA) axis reactivity. Psychoneuroendocrinology: 31(5):642-52.

    Oswald L, Zandi P, Nestadt G, Potash J, Kalaydijian A,  Wand, G.S. (2006) Relationship between cortisol responses to stress and personality. Neuropsychopharmacology: 31(7):1583-91.

    Uhart M, Oswald L, McCaul M, Chong R, Wand, G.S. (2006). Hormone responses and family history of alcoholism. Neuropsychopharmacology, In Press.

    Mangold D and Wand, G.S. (2006) Cortisol and ACTH responses to naloxone in subjects with high and low neuroticism. Biological Psychiatry, In Press.


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