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Center for Human Nutrition


Alain Labrique

Associate Professor
Dept of International Health / Dept of Epidemiology (jt)
Academic Degrees
PhD, Johns Hopkins School of Public Health (2007) MHS, Johns Hopkins School of Public Health, 1999 MSc, University of North Carolina at Chapel Hill, 1997
Departmental Affiliation
International Health
Global Disease Epidemiology and Control
Departmental Address
615 North Wolfe St., E5543
Baltimore, MD 21205
Phone: +1-443-287-4744
Fax: +1-410-510-1055
Research and Professional Experience

Curriculum Vitae (pdf)

Dr. Alain Labrique is an infectious disease epidemiologist by training, with a background in molecular biology. Dr. Labrique serves on the faculty in the Global Disease Epidemiology and Control Program of the Department of International Health, with a joint appointment in the Department of Epidemiology.  Having completed graduate research at UNC-Chapel Hill, studying centromere dynamics in yeast, Dr. Labrique shifted focus from the microscopic to human populations by pursuing a master’s and doctorate in Epidemiology at  the Johns Hopkins Bloomberg School of Public Health.

With colleagues at the ICDDR-B, Dr. Labrique conducted the first epidemiologic studies of hepatitis E virus infections in rural Bangladesh, characterizing this emerging pathogen. From 2001 to 2008, Dr. Labrique served as the resident JHU Project Scientist and Country Representative for the JiVitA Project, a large maternal and child health research project in northwestern rural Bangladesh, testing the impact of low-dose vitamin A supplementation during pregnancy and lactation on reducing maternal morbidity and mortality, as well as an infant mortality reduction trial through high-dose vitamin A supplementation of newborns.

In addition to teaching and mentoring students at the School, for which he was recently awarded an Excellence in Advising Award from President Ronald Daniels, and continued involvement as a Lead Investigator with the JiVitA micronutrient research projects, Dr. Labrique is working on defining the consequences of hepatitis E infections in pregnant women in South Asia, reducing nosocomial infections in hospitalized neonates, and exploring the role of intrapartum infections, such as bacterial vaginosis, on pregnancy outcomes and neonatal mortality. Dr. Labrique is also working to describe the “trajectories to mortality” in resource-limited settings experienced by women of reproductive age and infants, to identify novel opportunities for intervention.  Leading an interdisciplinary team spanning the Johns Hopkins University, Dr. Labrique and colleagues are exploring the potential for mobile information and communications technologies to facilitate timely emergency obstetric and neonatal care to reduce perinatal mortality and maternal morbidity in rural Bangladesh.

Dr. Labrique is also actively engaged in designing and exploring appropriate diagnostic and public health technologies, and is the inventor of a number of devices (3 patents pending), including the Portable Field Dark Adaptometer – a novel device currently being validated as a non-invasive method for vitamin A assessment.

Links to Lectures / Talks by Dr. Labrique (<-- CLICK HERE)


  • Center for Human Nutrition
  • Center for Global Health
  • International Injury Research Unit
  • Community Trials
  • Neonatal and Maternal Mortality
  • Mortality in Women of Reproductive Age (Violence)
  • Field research methods
  • Integrated Health Systems Technologies
  • Health seeking behavior
  • Hepatitis E (HEV)
  • Maternal Morbidity
  • Pregnancy and Infection
  • Evil Spirits and Infectious Diseases
  • Public Health Technology
  • Appropriate Technology
  • Assessment and Diagnostics
  • New Media and Public Health
  • mHealth and Mobile P...

Honors and Awards

Fellow, NIH mHealth Summer Institute, La Jolla, CA (2011), Johns Hopkins Faculty Innovation Fund Awardee (2011), President's Award for Excellence in Advising (2011), Inaugural Member, International Consortium for Control and Prevention of Viral Hepatitis E (2010), American College of Epidemiology (Elected Member, 2010) Delta Omega Inductee (2010), Johns Hopkins Center for Global Health Awardee (2008) Johns Hopkins Bloomberg School of Public Health Technology Transfer SEED Awardee (2005-2006) The David and Elinor Bodian Scholarship (JHU SPH) 2001-2002 Ruth Rice Puffer Award for International Students (JHU SPH) 2001 Charlotte Silverman Award for Outstanding Community Service (JHU SPH-Epidemiology) 2001 Delta Omega (Alpha Chapter) Scholarship Recipient 2001

Selected Publications

Book Chapters / Monographs 

1.     AB Labrique, J Katz. Community Intervention Trials. In: Cockerham, William C.(Ed.): Blackwell Encyclopedia of Health, Illness, Behavior, and Society. Wiley-Blackwell: Oxford, UK. 2013. (In press) 


2.     AB Labrique, A Dangour. Innovation. In: Steffen J, editor. Nutrition Security: A global perspective. Berkshire, UK; 2013. (In press)


3.     AB Labrique, A Hyder. Epidemiology of Drowning – The South and Southeast Asian Perspective. In: Bierens J, editor. Handbook on Drowning. Amsterdam, The Netherlands: Springer; 2011.


4.     AB Labrique, MH Kuniholm, KE Nelson. The global impact of Hepatitis E – new horizons for an emerging virus. In: Scheld WM, Murray BE, Hughes JM, editors. Emerging Infections. 9th Edition. Virginia: ASM Press; 2010.

5.     AB Labrique, HE Elnaggar. The Grameen Experience, 1992. Grameen Bank: Dhaka, Bangladesh.


1.     AB Labrique, KP West, Jr. A. Sommer. A Portable Field Dark Adaptometer. July 30, 2010. Johns Hopkins University, Baltimore, MD, USA. Provisional Patent Number 61/369,283.

2.     AB Labrique. Automatic, Digital MUAC (Mid-Upper Arm Circumference) Measurement. Johns Hopkins University, Baltimore, MD, USA. Provisional Patent Number  61/424,369.

1.     AB Labrique, S Shaikh, KP West, Jr. Portable Acrylic Infant Length Board. February, 2011. Johns Hopkins University, Baltimore, MD, USA. Provisional Patent Number 61/450,949.

Peer Reviewed Journal Articles*

1.     AB Labrique, K Zaman, M Yunus, Z Hossain, A Hossain, T Azim, J Ticehurst, KE Nelson. Epidemiology of acute hepatitis E illness in a rural population – a case control study. (PLOS One, In Press).

2.     *Sowapak  H, Nelson KE, Gibbons RV, Jarman RG, Chinnawirotpisan P, Tablerk P, Smithsuwan P, Labrique AB. A cross sectional study of hepatitis E virus infection in pigs in different sized farms in Northern Thailand (Vet Research, In Press)


3.     * Z Hossain, S Sikder, K Zaman, P Saha, M Yunus, AB Labrique. Local perceptions and care seeking associated with jaundice in Matlab, Bangladesh. (JHPN, In Press).


4.     *Kmush B, Wierzba T, Krain L, Nelson KE, Labrique AB. Epidemiology of Hepatitis E in Low and Middle Income Countries of Asia and Africa. (Seminars in Liver Disease, In Press)


5.     *M Sundaram, AB Labrique, S Mehra, H Ali, AA Shamim, RDW Klemm, KP West, Jr, P Christian. Early newborn feeding is common and associated with breastfeeding behavior in rural Bangladesh. (J Nutr, In Press).

6.     Shamim AA, Kabir A, Merrill RD, Ali H, Rashid M, Schulze K, Labrique AB, West KP, Jr., Christian P. Plasma zinc, B12 and α-tocopherol are positively and γ-tocopherol negatively associated with hemoglobin concentration in early pregnancy in northwest Bangladesh. (J Nutr, In Press).


7.     Klemm RDW, Merrill RD, Wu L, Shamim AA, Ali H, Labrique AB, Christian P, West KP Jr.  Low birth weights higher among Bangladeshi neonates measured during active birth surveillance compared to national survey data. February 2013 (Maternal and Child Nutrition, In Press)


8.     *Varma G, Savard P, Coles C, Ross T, Carroll K, Perl T, Labrique AB. Hospital room sterilization using far-UV radiation: a pilot evaluation of the Sterilray® device in an active hospital setting. (Inf Control and Hosp Epid, In Press)


9.     *Kaonga NN, Labrique AB, Mechael PN, Akosah E, Ohemeng-Dapaah S, Sakyi-Baah J, Kodie R, Kanter AS and O Levine.  Using Social Networking to Understand Social Networks: An Analysis of a Mobile Phone Closed User Group used by a Ghanaian Health Team.  (Journal of Medical Internet Research, In Press)


10.  *H Sowapak, KE Nelson, RV Gibbons, RG Jarman, D Mongkolsirichaikul, P Smithsuwan, S Fernandez, AB Labrique, P Patchanee. A cross-sectional study of hepatitis E virus infection in healthy people directly exposed and unexposed to pigs in a rural community in Northern Thailand. (Zoonoses and Pub Hlth, In Press)


11.  *Sikder SS, AB Labrique, Rashid M, West KP, Jr., Ali H, Shamim AA, Christian P. (2011). Beyond pregnancy: the neglected burden of female mortality in young women of reproductive age in South Asia. (BJOG, In Press)   


12.  AB Labrique, S. Sikder, L.J.Krain, K.P. West, Jr., P. Christian, M. Rashid, K.E. Nelson. Hepatitis E, a Vaccine Preventable Cause of Maternal Deaths. Emerg Infect Dis. 2012 Sep;18(9):1401-4. doi: 10.3201/eid1809.120241.

13.  Christian P, Klemm K, Shamim AA, Al i H, Rashid M, Shaikh S, Wu L, Mehra S, Labrique AB, Katz J, West KP Jr. Effects of vitamin A and β-carotene supplementation on birth size and length of gestation in rural Bangladesh: a cluster-randomized trial. Am J Clin Nutr. 2013 Jan;97(1):188-94. doi: 10.3945/ajcn. 112.042275. Epub 2012 Nov 14.

14.  *Sikder SS, Labrique AB, Ullah B, Mehra S, Rashid M, Ali H, Jahan N, Shamim AA, West KP, Jr, Christian P. Care-seeking patterns for fatal non-communicable diseases among women of reproductive age in rural northwest Bangladesh. BMC Womens Health. 2012 Aug 15;12:23-29. doi: 10.1186/1472-6874-12-23.


15.  *Kim J, Labrique AB, West, KP Jr, Rashid M, Shamim AA, Ali H, Ullah B, Wu L, Massie A,  Mehra S, Klemm R, Christian P. Maternal Morbidity in Early Pregnancy in Rural Northern Bangladesh. Int J Gynaecol Obstet. 2012 Dec;119(3):227-33. doi: 10.1016/j.ijgo.2012.06.022. Epub 2012 Oct 2.


16.  Merrill R, Shamim A, Ali H, Labrique AB, Schulze K, Christian P, West KP Jr. High prevalence of anemia with lack of iron deficiency among women in rural Bangladesh: a role for thalassemia and iron in groundwater. Asia Pac J Clin Nutr 2012;21:416-4


17.  Gernand AJ, Christian P, Schulze K, Shaikh S, Labrique AB, Shamim AA, West KP Jr. Maternal nutritional status in early pregnancy is associated with body water and plasma volume changes in a pregnancy cohort in rural Bangladesh. J Nutr 2012 142:1109-15.


18.  Gernand AJ, Christian P, Paul RR, Shaikh S, Labrique AB, Schulze KJ, Shamim AA, West KP Jr.. J Nutr. 2012 Nov;142(11):2010-6. doi: 10.3945/jn.112.163634. Epub 2012 Sep 18.


19.  R Merrill,  AA Shamim, H Ali, N Jahan, AB Labrique, P Christian, KP West, Jr. Groundwater iron assessment and consumption by women in rural northwestern Bangladesh. Int J Vitam Nutr Res. 2012 Feb;82(1):5-14. doi: 10.1024/0300-9831/a000089.


20.  S Shaikh, KJ Schulze, A Kurpad, H Ali, AA Shamim, S Mehra, L S-F Wu, M Rashid, AB Labrique, P Christian, KP West, Jr.  Development of bioelectrical impedance analysis based equations for estimation of body composition in postpartum rural Bangladeshi women. Br J Nutr. 2012 May 4:1-9. [Epub ahead of print]


21.  * S Sikder,  AB Labrique, , B Ullah, H Ali, M Rashid, S Mehra, N Jahan, AA Shamim, KP West Jr, P Christian. Accounts of Severe Acute Obstetric Complications in Rural Bangladesh. BMC Pregnancy Childbirth. 2011 Oct 21;11(1):76.


22.  * KE Nelson, B Kmush, AB Labrique. The epidemiology of Hepatitis E virus infections in developed countries and among immunocompromised patients. Expert Rev Anti Infect Ther. 2011 Dec;9(12):1133-48.


**P Christian, AB Labrique, H Ali, M Richman, L Wu, M Rashid, KP West, Jr., Maternal vitamin A and beta-carotene supplementation and risk of bacterial vaginosis. A randomized controlled trial in rural Bangladesh. Am J Clin Nutr. 2011 Dec;94(6):1643-9. Epub 2011 Nov 9.

24.  ** C Coles, A Labrique, SK Saha, H Ali, H Al-Emran, M Rashid, P Christian, KP West, Jr., R Klemm. Newborn Vitamin A Supplementation Does Not Affect Nasopharyngeal Carriage of Streptococcus pneumoniae in Bangladeshi Infants at Age 3 Months. 2011. J Nutr. doi:10.3945/jn.111.141622


25.  S Shaikh, KJ Schulze, H Ali, AB Labrique, AA Shamim, M Rashid, S Mehra, P Christian, KP West, Jr. Bioelectrical impedance among rural Bangladeshi Women during pregnancy and in the postpartum period. J Health Popul Nutr. 2011 Jun;29(3):236-44.

26.  RD Merrill, AA Shamim, H Ali, N Jahan, AB Labrique, K Schulze, P Christian, KP West, Jr., Iron Status of Women Is Associated with the Iron Concentration of Potable Groundwater in Rural Bangladesh. Journal of Nutrition, 2011. jn.111.138628


27.  AB Labrique, P Christian,  RDW Klemm, M Rashid, AA Shamim, A Massie, K Schulze, A Hackman, KP West, Jr. A Cluster-Randomized Maternal Vitamin A or Beta-Carotene Supplementation Trial in Bangladesh: Design and Methods. Trials, 2011. 12:102

28.  ** KP West, Jr., P Christian, AB Labrique, M Rashid, AA Shamim, RDW Klemm, A Massie, S Mehra, K Schulze, H Ali, B Ullah, L Wu, J Katz, H Banu, A Sommer. Vitamin A or beta-carotene supplementation and mortality related to pregnancy: A cluster-randomized, double-masked, placebo-controlled trial in Bangladesh.  JAMA. 2011; 305(19): 1986-1995.


29.  RD Merrill, AA Shamim, H Ali, N Jahan, AB Labrique, P Christian, KP West, Jr. Iron status of women is associated with the iron concentration of potable groundwater in rural Bangladesh. J Nutr. 2011 May;141(5):944-9. Epub 2011 Mar 30.


30.  *J Sugimoto, AB Labrique, S Ahmad, M Rashid, AA Shamim, B Ullah, RDW Klemm, P Christian, KP West, Jr. Epidemiology of a tornado in rural northern Bangladesh: Risk factors for death and injury. Disasters 2011; 35(2); 329-345.

31.  AA Shamim, P Christian, KJ Schulze, H Ali, A Kabir, M Rashid, AB Labrique, Q Salamatullah, KP West Jr. Iodine status in pregnancy and household salt iodine content in rural Bangladesh. Matern Child Nutr. 2010 Oct 26. doi: 10.1111/j.1740-8709.2010.00282.x.

32.  AB Labrique, K Zaman, Z Hossain, P Saha, M Yunus, A Hossain, J Ticehurst, KE Nelson. Epidemiology and Risk Factors of Incident Hepatitis E Virus Infections in Rural Bangladesh. AJE. 2010 Aug; 172(8): 952-961.


33.  * S Gunnsteinsson, AB Labrique, KP West Jr., P Christian, S Mehra, AA Shamim, M Rashid, J Katz, RDW Klemm. Constructing indices of rural living standards in Northwestern Bangladesh. JHPN. 2010 Oct; 28(5):509-519.


34.  ** MW Merritt, AB Labrique, J Katz, KP West, Jr., J Pettit. A Field Training Guide for Human Subjects Research Ethics. PLoS Med. 2010; 7 (10). e1000349.

35.  * RD Merrill, AB Labrique, AA Shamim, K Schulze, P Christian, RK Merrill, KP West, Jr. Elevated and variable groundwater iron in rural northwest Bangladesh. Journal of Water and Health. 8: 818-825. 2010.

36.  * MH Kuniholm, AB Labrique, KE Nelson. Should HIV-Infected Patients with Unexplained Chronic Liver Enzyme Elevations Be Tested For Hepatitis E Virus ? Clinical Infectious Diseases. 2010 Jun 1; 50(11): 1545-6.


37.  JH Rah, AA Shamim, UT Arju, AB Labrique, RDW Klemm, M Rashid, P Christian. Difference in ponderal growth and body composition among pregnant versus never-pregnant adolescents varies by birth outcomes. Maternal and Child Nutrition. 6(1). 27-37(11). January 2010.


38.  AB Labrique, K Zaman, M Yunus, Z Hossain, A Hossain, T Azim, J Ticehurst, KE Nelson. Seroprevalence of HEV antibodies in rural Bangladesh. Am J Trop Med Hyg. 81(5). p875-881. 2009.


39.  JH Rah, AA Shamim, UT Arju, AB Labrique, M Rashid, P Christian. h. JHPN 2009 Dec; 27(6). 802-807.


40.  JH Rah, AA Shamim, UT Arju, AB Labrique, RDW Klemm, M Rashid, P Christian. Predictors of stunting and thinness in post-menarcheal adolescent girls in rural Bangladesh. Public Health Nutrition. 12(12), 2400-2409. 2009.

41.  RD Merrill, AA Shamim, AB Labrique, H Ali, K Schulze, M Rashid, P Christian, K.P. West, Jr. Validation of Two Portable Instruments to Measure Iron Concentration in Groundwater in Rural Bangladesh. JPHN 2009; 27(3):414-8.

42.  JH Rah, P Christian, AA Shamim, UT Arju, AB Labrique, M Rashid. Pregnancy and Lactation Hinder Growth and Nutritional Status of Adolescent Girls in Rural Bangladesh. J Nutr. 2008; 138: 1505-1511.

43.  ** RW Klemm, AB Labrique, P Christian, M Rashid, AA Shamim, J Katz, A Sommer, KP West Jr. Newborn Vitamin A Supplementation Reduced Infant Mortality in Rural Bangladesh, Pediatrics 2008; 122; e242-e250.

44.  * JD Sugimoto, AB Labrique, S Ahmad, M Rashid, RW Klemm, P Christian, KP West Jr. Development and Management of a Geographic Information System for Health Research in a Developing-country Setting: A Case Study from Bangladesh. JHPN 2007: 25(4):436-447.

45.  * JD Sugimoto, S Ahmad, M Rashid, AA Shamim, AB Labrique. A Low-cost Method to Identify Tubewells for Longitudinal Research on Arsenic in Groundwater. JHPN 2007: 25(3):377-381.

46.  C Beyrer, MH Razak, AB Labrique, R Brookmeyer.  Assessing the magnitude of the HIV/AIDS epidemic in Burma. J Acquir Immune Defic Syndr. 2003 Mar 1;32(3):311-7.

, DL Thomas, SK Stoszek, KE Nelson. Hepatitis E: An Emerging Infectious Disease. Epidemiologic Reviews. Vol.21(2): 162-179. 1999.

Group / Committee Authorship

1.     Fraser H, Bailey C, Sinha C, Mehl G, AB Labrique and the Bellagio eHealth Evaluation Group. Call to Action on Global eHealth Evaluation. Consensus Statement of the WHO Global eHealth Evaluation Meeting, Bellagio, Italy. September 2011.

Letters / Commentaries

1.     AB Labrique, L Vasudevan, LW Chang, G Mehl. H_pe for mHealth: More “y” or “o” on the horizon? (International Journal of Med Informatics, 2013, In Press)


2.     AB Labrique, S Pereira, P Christian, N Murthy, L Bartlett, G Mehl. Pregnancy registration systems can enhance health systems, increase accountability and reduce mortality. Reprod Health Matters. 2012 Jun;20(39):113-7. doi: 10.1016/S0968-8080(12)39631-6.


3.     AB Labrique, Sikder SS, Mehra S, Wu L, Huq R, Ali H, Christian P,  West KP, Jr. Mobile phone ownership and widespread mHealth use in 168,231 women of reproductive age in rural Bangladesh (2012). Journal of Mobile Technology in Medicine (4S): 26.

4.     AB Labrique, MW Merritt, LA Bartlett., Cultural and contextual challenges to validating consent to research. JAMA. 2011 Jul 20;306(3):266.

5.     ** KP West Jr., P Christian, J Katz, AB Labrique, R Klemm, A Sommer. Effect of vitamin A supplementation on maternal survival. The Lancet. 2010; 376(9744); 873-874.

6.     AB Labrique, WK Pan. Diagnostic Tests: Understanding results, assessing utility and predicting performance (Editorial). Am J Opthalmol. 2010 Jun; 149(6):878-881.e2.

7.     AB Labrique, KE Nelson. Hepatitis E Virus Infections Among U.S. Military Personnel Deployed to Afghanistan. JID. 2010; 202(9); 1297-9.


** KP West Jr, P Christian, R Klemm, AB Labrique, M Rashid, AA Shamim, J Katz, A Sommer. The JiVitA Bangladesh Project: Research to improve nutrition and health among mothers and infants in rural South Asia. Sight and Life, Newsletter 1/2006. PO box 2116, 4002 Basel, Switzerland.