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Institutional Review Board


PHIRST (Public Health Institutional Review Submission and Tracking) is a web-based system used by the Johns Hopkins Bloomberg School of Public Health Institutional Review Board (JHSPH IRB) as a portal for all new human subjects research applications. The original PHIRST system (“Old PHIRST”) went live in 2006.

Starting December 10, 2019, an upgraded PHIRST system (new PHIRST, or PHIRST2.0) goes live. This new version will handle not only new studies, but amendments, continuing review/progress reports and other reporting to the JHSPH IRB. A study’s whole file will exist in PHIRST2.0.

OLD PHIRST: Studies initially submitted in Old PHIRST will still be available to investigators; no new studies can go through this system after Dec. 6, 2019. Studies under review will complete processing in Old PHIRST, and then will move to PHIRST2.0. Co-investigators and study team members for these studies can still register in Old PHIRST if needed. Log in to Old PHIRST:

PHIRST (PHIRST2.0): Applications approved in Old PHIRST will have a “shell” in the new system that will facilitate transition to the new system. These shells can be populated with currently approved study documents, and once all the questions are completed, be submitted to the JHSPH IRB. (See the Completing Study Shells User Guide).The IRB will check the application over and activate it. Once activated, Principal Investigators will submit all future continuing review/progress reports, amendments, etc. through PHIRST. Log in to new PHIRST:

If you have any questions or problems with the PHIRST registration process or the information in the PHIRST User Guide, please contact the PHIRST Help Desk at

While we transition to PHIRST2.0, these PHIRST FAQs may help you plan your study submissions. Contact with your questions.