The Value of Immunization Compendium of Evidence (VoICE 


The mortal burden of vaccine-preventable disease, and the impact of vaccines on mortality, have long been the centerpiece of messaging used by advocates to bolster support for robust immunization programs in low- and lower-middle-income countries (LMICs). However, in the past 10 years, as a global economic crisis has unfolded, competition for donor investment and focus on a broader array of measures of success have increased, professional advocates have articulated a need to move beyond messages about mortality to evidence-based messages illustrating the broad and long-lasting impact of vaccines on economies, societies and households. 


The Value of Immunization Compendium of Evidence (VoICE), found at, is a searchable database intended to support immunization, child health and global health advocates by synthesizing evidence of the broader value of vaccines. The compendium contains ideas and evidence illustrating the impact that vaccines, and vaccine-preventable diseases, can have on the health, economic status, societal well-being, equity, and other factors affecting families and nations worldwide. The VoICE team at IVAC works to identify and synthesize evidence from peer reviewed articles and other high-quality sources to continuously add new content to the compendium. The VoICE tool contains more than 450 key ideas, data summaries and sources – with more added each week – illustrating the broad value of immunization and toll of vaccine-preventable disease as organized under 6 primary topic areas and more than 25 subtopics. 

The VoICE team also develops cross-cutting evidence syntheses that describe the arc of the relationship between vaccination and a given topic, such as pneumonia, poverty or nutrition. Here, we’re able to connect evidence from VoICE – and external experts – across the societal, economic and health spectrums to illustrate the breadth and depth of immunization’s value with respect to a given topic.  

  • Searchable compendium with value of vaccine evidence, organized into overarching concepts and summarized results, to support these 6 topics: education, economics, health, health systems, equity, and pressing global issues  
  • Cross-cutting narratives featuring timely topics of relevance to professional advocates
  • Media library featuring a free-to-use collection of data visualizations, images, videos, and social media content