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Functions of the SMC5/6 complex


Summary

SMC5/6 is the least studied SMC protein complex. Our lab is using conditional knockout alleles of Smc5 to delineate the role of the SMC5/6 complex using four different cellular platforms: 1) Spermatogenesis, 2) Oogenesis, 3) Embryonic stem cells and 4) Neurodevelopment. Using these approaches, we are defining the roles of SMC5/6 during mitotic and meiotic cell cycle progression. We are also determining the protein interaction network of the SMC5/6 complex.

Dates

  • Start Date: 
    03/01/2013

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