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Male Circumcision Trial For Hiv Prevention, Rakai, Uganda (through the Rakai Health Services Program)


Summary

This is a DAIDS funded randomized trial of 5000 HIV-negative men who accept VCT. Men are randomized to receive immediate circumcision (intervention arm), or circumcision delayed for two years (control arm). The trial endpoints are HIV incidence in circumcised versus uncircumcised men, and the safety of circumcision. Secondary endpoints include effects of circumcision on STIs (syphilis, HSV-2, HPV, gonorrhea and Chlamydia), and sexual risk behaviors. Enrollment was completed in July, 2005 and an interim analysis was done in June, 2006. A further interim analysis was requested by the DSMB for December, 2006. Assuming the continuation of the trial, follow up will be completed by July, 2007.

For more information on the Rakai Health Sciences Program, please visit our website: www.jhsph.edu/rakai/

Dates

  • Start Date: 
    09/15/2002
  • End Date: 
    09/30/2008

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