Statins as Adjunctive Therapy for Tuberculosis (StAT-TB)
Johannesburg, South Africa
The goal of this study is to investigate the potential utility of pravastatin as an adjunctive, host-directed therapy for drug-susceptible pulmonary TB in a two-stage randomized control trial. Stage 1 is a 30-day PK/tolerability study and Stage 2 is a 12-month efficacy study. The primary outcomes will be safety/toxicity, median time to sputum culture conversion, and lung function outcomes.
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- Johannesburg, South Africa: 19 projects - selected city