Eye Determinants of Cognition (EyeDOC) Study
Hagerstown, MD, United States
The EyeDOC study is examining the relationship between retinal health and cognitive function. Dementia and mild cognitive impairment pose enormous health and societal costs in our aging U.S. population. While cerebral neural loss is known to contribute to Alzheimer's dementia, vascular diseases may contribute substantially to the total burden of dementia and its precursor, mild cognitive impairment (MCI), which is an intermediate stage between the expected cognitive decline of normal aging and the more serious decline of dementia.
The eye may be a unique window to otherwise unobservable brain pathology responsible for diseases that affect cognition such as Alzheimer's disease. State-of-the-art Optical Coherence Tomography (OCT) imaging can now capture markers of both neurodegenerative and microvascular disease in the retina.
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