Skip Navigation

Research

Global Projects

Map

Phase 2 Adherence and Pharmacokinetics Study of Oral and Vaginal Preparations of Tenofovir

Cleveland, OH, United States


Summary

International, multi-center study of the Microbicide Trials Network (MTN) designed to compare the pharmacokinetics and adherence to regimen of two methods of delivering HIV prevention medication to women at risk of HIV infection. Subjects will be randomized to sequence of oral tenofovir, vaginal tenofovir, or both oral and vaginal tenofovir. Outcomes are pharmacokinetics and adherence to dosing regimen. Six centers in South Africa, Uganda, and the US are participating. The study will inform future design of comparative studies of PrEP and microbicide s as HIV prevention strategies.

Dates

  • Start Date: 
    01/01/2008
  • End Date: 
    06/30/2010

Locations

Centers