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Environmental Exposures and Cognitive Decline, Dementia, and Alzheimer's Disease Among Middle to Old Age Black Men in the United States

Baltimore, MD, United States


Unique and compounded environmental exposures may lead to the poor cognition and increased risk of dementia and Alzheimer’s disease (AD) among Black men, and psychosocial stressors commonly associated with health disparities may amplify the effects of environmental exposures in this vulnerable population. We propose to link hazardous air pollutant models based on geocoded addresses to longitudinal cohort data from Black men enrolled in the Health and Retirement Study (HRS) to investigate associations residential ambient air pollutant concentrations and age-adjusted risk of cognitive impairment, dementia, and AD, then identify the role of psychosocial stressors in this relationship. This research is ground-breaking from both a scientific and justice perspective and promises to generate new insights into the mechanisms of the disproportionate burden of illness in this particularly vulnerable demographic group.


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