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Global Projects


Smoking and Tuberculosis

Karachi, Pakistan


There is growing evidence that tobacco smoking increases tuberculosis (TB) infection, disease and mortality, and that tobacco use may decrease the effectiveness of TB treatment leading to higher rates of relapse. Despite this growing evidence base, however, there is limited data on the effectiveness of smoking prevention and cessation on TB outcomes.

The overall objective of this study is to investigate the prevalence of smoking among men and women who have been recently diagnosed with tuberculosis (TB) in diverse international settings which represent different TB epidemics in terms of burden and epidemiology. A smoking prevalence survey modified from the CDC GATS survey was given in representative settings and populations in South Africa, Pakistan and Georgia.

These countries represent different TB epidemics in terms of burden and epidemiology. Together these countries are representative of the epidemiologic picture of global TB and it is likely that the tobacco epidemic is different in each. Thus, determining prevalence of smoking among TB patients is integral towards determining the potential impact of integrating smoking cessation into Direct Observed Therapy (DOTS) programs in each country. This study will provide preliminary data for future studies investigating smoking cessation strategies for these patient groups.