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Identifying Environmental Transmission Routes for Shigellosis in Rural Settings using Pulsed-field Gel Electrophoresis

Mirzapur, Bangladesh


The primary aim of this multidisciplinary investigation across the Whiting School of Engineering and the Bloomberg School of Public Health is to conduct the first evaluation of environmental transmission of Shigella in a rural setting using Pulsed field gel Electrophoresis. The secondary aim is to investigate the transport dynamics of Shigella in these communities, particularly the relationship between poor sanitation and Shigella in shallow groundwater aquifers utilized for drinking. To achieve these aims we are conducting a prospective cohort study of household contacts of shigellosis cases and household contacts of community controls in rural Mirzapur, Bangladesh.