624 N. Broadway
Hampton House 850
Baltimore, Maryland 21205
PhD, Case Western Reserve University, 2000
I am interested in applying genetic epidemiology methods to studies of neuropsychiatric disorders including autism, Alzheimer's disease, schizophrenia, and bipolar disorder and to developing applications and methods for epigenetic epidemiology, particulary as applied to mental health and development.
The goal of my research is to understand the genetic and environmental causes of neuropsychiatric diseases and their interplay. Specifically, my group studies how environments, behaviors, genetic variation, and epigenetic variation contribute to risk for psychiatric disease, particularly autism. I have training in both epidemiology and statistical genetics, and have worked on methodological developments for genetic epidemiology studies as well as led recruitment efforts for general epidemiological projects in autism and Alzheimer’s disease. I was the past Director of the Genetic Epidemiology Program in the Department of Epidemiology at Johns Hopkins and am now the Chair of the Department of Mental Health in the same Bloomberg School of Public Health and Director of the Wendy Klag Center for Autism and Developmental Disabilities. I am PI of the Maryland site of the SEED study (Study to Explore Early Development), a multi-site case-control study of autism genetic and environmental risk factors and the EARLI study (Early Autism Research Longitudinal Investigation), a prospective pregnancy cohort focused on causes of autism. I also co-PI the conversion of the Boston Birth Cohort into an autism prospective birth cohort via HRSA funding. I have led GWAS and EWAS (epigenome-wide) projects for autism based on SEED and EARLI samples and co-led two NIH Roadmap-funded projects on epigenetic epidemiology.