615 N. Wolfe Street
Baltimore, Maryland 21205
PhD, New York University, 1978
MSc, New York University, 1974
Our research focuses on molecular biomonitoring of toxic agents and genetic polymorphisms associated with their metabolism. The general theme is the assessment of toxicant metabolites and early effects in human populations with known or suspected exposure to various occupational or environmental toxicants. This approach has widespread application in assessing previous exposure to carcinogens and other toxicants and is used as a predictor of ultimate disease risk. The ability to measure toxicant metabolites and early effects in human tissues allows one to address a variety of public health issues related to the human exposome and individual susceptibility to environmental diseases. Furthermore, elucidating the spectrum of common polymorphisms in toxicant metabolizing and other genes associated with disease outcome provides an approach to assessing individual susceptibility to disease.
International Agency for Research on Cancer Fellow (UK); Dale Research Fellow (Paterson Laboratories, UK); Mellon Foundation Fellow (Johns Hopkins University); Howard Fox Lecture, New York University Medical Center, New York; Keynote Lecture, International Symposium on Biological Monitoring, Seoul, Korea; Keynote Lecture, International Symposium on Occupational Health, Bangkok, Thailand
Selected Publications from the last 5 years.