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Peter P. Zandi, PhD

  • Professor

Departmental Affiliations

Contact Information

624 N. Broadway
Hampton House 857
Baltimore, Maryland 21205


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PhD, Johns Hopkins Bloomberg School of Public Health, 2001
MHS, Johns Hopkins Bloomberg School of Public Health, 2000
MPH, Johns Hopkins Bloomberg School of Public Health, 1997


I have several research interests.  I am interested in the genetic epidemiology of psychiatric disorders, including mood disorders and Alzheimer's disease.  The goal of my research in this area is to identify the genetic causes of these disorders and determine how genetic and environmental factors interact to shape susceptibility.  I am also interested in the pharmacoepidemiology of Alzheimer's disease and mood disorders. I am engaged in both observational and randomized studies to develop and evaluate pharmacological strategies for treatment and/or prevention of these disorders.  Finally, I am interested in the pharmacogenetics of psychotropic medications.  This interest brings together the previous two lines of research to examine how genetic factors influence safety and efficacy responses to pharmacological treatments in patients with psychiatric disorders.

Honors and Awards

Delta Omega Society, Alpha Chapter (2002)

The Morton Kramer Award for the Application of Biostatistics and Epidemiology in Research on the Prevention and Control of Mental Disorders, Department of Mental Hygiene (2000)

Distinguished Guest Student, The Lasker Award Ceremony (2000)

The Harold and Sylvia Halpert Award, Department of Mental Hygiene (1999)

NIMH pre-doctoral fellowship in psychiatric epidemiology (1998)

  • Genetic Epidemiology, Pharmacoepidemiology, Pharmacogenetics, Alzheimer's Disease, Mood Disorders, Autism
  • Chuang YF, Hayden KM, Norton MC, Tschanz J, Breitner JC, Welsh-Bohmer KA, Zandi PP, for the Cache County Investigators. The Association between APOE and vascular dementia: The Cache County Study. Dementia and Geriatric Cognitive Disorders. 2010;29(3):248-53.

  • Zandi PP, Judy JT. The promise and reality of pharmacogenetics in psychiatry. Psychiatric Clinics of North America. 2010;33(1):181-224.

  • Szekely CA, Green RC, Breitner JC, Østbye T, Beiser AS, Corrada MM, Dodge HH, Ganguli M, Kawas CH, Kuller LH, Psaty BM, Resnick SM, Wolf PA, Zonderman AB, Welsh-Bohmer KA, Zandi PP. No advantage of A beta 42-lowering NSAIDs for prevention of Alzheimer dementia in six pooled cohort studies. Neurology. 2008;70(24):2291-8.

  • Zandi PP, Belmonte PL, Willour VL, Goes FS, Badner JA, Simpson SG, Gershon ES, McMahon FJ, DePaulo JR Jr, Potash JB; Bipolar Disorder Phenome Group; National Institute of Mental Health Genetics Initiative Bipolar Disorder Consortium. Association study of Wnt signaling pathway genes in bipolar disorder. Archives of General Psychiatry. 2008;65(7):785-93.

  • Zandi PP, Zöllner S, Avramopoulos D, Willour VL, Chen Y, Qin ZS, Burmeister M, Miao K, Gopalakrishnan S, McEachin R, Potash JB, Depaulo JR Jr, McInnis MG. Family-based SNP association study on 8q24 in bipolar disorder. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics). 2008;147B(5):612-18.

  • Bayesian Hierarchical Models for Individualized Health