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Renan Castillo, PhD

  • Associate Professor

Departmental Affiliations

Center & Institute Affiliations

Contact Information

624 N. Broadway
Hampton House 543
Baltimore, Maryland 21205


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PhD, Johns Hopkins Bloomberg School of Public Health, 2008
MS, Johns Hopkins University, 1997
BA, Johns Hopkins University, 1993


Trauma Outcomes. Orthopedic Trauma. Clinical Trials, Pain and Psychologic Distress. Structural Models. Health Disparities. Cognitive Behavioral Therapy. Self Management Interventions.

Honors and Awards

2004 Orthopedic Trauma Association Annual Meeting: Paper selected for presentation at Specialty Day at the American Academy of Orthopedic Surgeons

American Academy of Orthopedic Surgeons 2003 Ann Doner Vaugham Kappa Delta Award for Best Research Project (as part of the LEAP research team).

2003 Orthopedic Trauma Association Annual Meeting: Paper selected for presentation at Specialty Day at the American Academy of Orthopedic Surgeons.


  • Trauma Outcomes, Pain, Structural Equation Modeling, Disparities, Cognitive Behavioral Therapy, Self Management Interventions

    Castillo RC, Wegener ST, Heins SE, Haythornthwaite JA, Mackenzie EJ, Bosse MJ; the LEAP Study Group. Longitudinal relationships between anxiety, depression, and pain: Results from a two-year cohort study of lower extremity trauma patients. Pain, 154(12):2860-6, Aug 29 2013.



    Castillo RC, Wegener ST, Newell MZ, Carlini AR, Bradford AN, Heins SE, Pollak AN, Teter H, MacKenzie EJ. Improving outcomes at Level I trauma centers: an early evaluation of the Trauma Survivors Network. Journal of Trauma and Acute Care Surgery; 74(6):1534-40, Jun 2013.



    Castillo RC, MacKenzie EJ, Bosse MJ. Measurement of Functional Outcomes in the Major Extremity Trauma Research Consortium (METRC). Journal of the American Academy of Orthopaedic Surgery. 2012;20 Suppl 1:S59-63. doi: 10.5435/JAAOS-20-08-S59.



    Castillo RC, Scharfstein DO, MacKenzie EJ. Observational studies in the era of Randomized Trials: Finding the Balance.  Journal of Bone and Joint Surgery. 2012 Jul 18;94 Suppl 1:112-7.



    Castillo RC, Bosse MJ, MacKenzie EJ, and the LEAP study group. “Orthopaedic Trauma Clinical Research: Is Two Year Follow-up Necessary? Results from a Longitudinal Study of Severe Lower Extremity Trauma.” Journal of Orthopaedic Trauma. 2011 Dec;71(6):1726-31.


  • Assessing Barriers to Implementation of the Trauma Survivors Network
  • Development of a Screening Tool for Delayed Return to Work Following Low Back Injuries
  • Improving Trauma Outcomes: A Patient-Centered Approach
  • Novel Therapy to Reduce Infection after Operative Treatment of Fractures at High Risk of Infection: A Multicenter Randomized Controlled Trial
  • Qualitative Assessment of the Benefits of Peer Visitation
  • Reliability and Responsiveness of PROMIS tools in Orthopaedic Trauma Patients
  • Supplemental Perioperative Oxygen to Reduce Surgical Site Infection in At-Risk Fracture Surgery
  • The Major Extremity Trauma and Rehabilitation Consortium
  • Treatment of Early Post-Op Wound Infection after Plate Internal Fixation
  • Validation of PROMIS for Orthopaedic Trauma Research