PhD, Johns Hopkins University, 2000
BS, University of North Carolina, Chapel Hill, 1987
As the Director of Epidemiology for IVAC (International Vaccine Access Center), focus on the technical analytical challenges of policy-driven research pertaining to the design, conduct and analysis of epidemiological studies and clinical trials that evaluate vaccines and vaccine-preventable diseases. I direct the analysis of a 7-country pneumonia case-control study (PERCH) to determine the causes of pneumonia in developing country settings to guide the development of new pneumonia vaccines and treatment algorithms. Multiple projects have involved evaluating the impact of pneumococcal conjugate vaccine introduction into national immunization programs in India, Nepal, Kenya and The Gambia on pneumococcal disease, and in global assessments of its impact. I also have an interest in evaluating new diagnostic tools such as antigen-based blood tests and pneumococcal serotype-specific urine antigen tests for sensitivity and specificity of disease detection in pneumonia patients, and digital tools to assist in the standardization of clinical findings, such as digital auscultation and computer automated chest x-ray interpretation. I also work on collaborative efforts with other Departments and Institutions to develop new analytical tools, such as an analytical method for estimating pneumonia etiology. Secondary data analysis projects include global meta-analytical projects to estimate disease burden and vaccine impact, such as estimating the burden and serotype distribution of pneumococcal, Hib and meningococcal disease among children and adults, and evaluation of pneumococcal conjugate vaccine schedules and products to inform country decision-making regarding these programmatic choices.
Honors and Awards
National Institutes of Health Merit Award (1999,1991)
Food and Drug Administration Commissioner’s Special Citation Group Award (1997)
U.S. DHHS Secretary’s Group Award for Distinguished Service (1996)
U.S. DHHS Special Achievement Award (1995,1991)