Research is focused on child health in developimg countries, especially diarrheal and respiratory diseases. This has included clinical trials of improved and simplified treatments for acute diarrhea and cholera, including oral rehydration therapy, and on the evaluation of vaccines for cholera, typhoid fever, rotavirus, Haemophilus influenzae type b, and pneumococcal disease. Current collaboration is with the World Health Organization Department of Child and Adolescent Health and Development. Previous research was on mucosal immunity inanimal models, studying especially the cellular kinetics of the intestinal IgA immune response and determinants of the mucosal distribution of that response.
Honors and Awards
Research Career Development Award - 1971-1976 Pollin Prize in Pediatric Research - 2002