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Caleb Alexander, MD

  • Professor

Departmental Affiliations

  • Epidemiology (Primary)
    • Division: General Epidemiology and Methodology
  • School of Medicine (Joint)

Center & Institute Affiliations

Contact Information

615 N. Wolfe Street
Room W6035
Baltimore, Maryland 21205

410 955 0863

Center for Drug Safety and Effectiveness
August 3, 2018 Testimony on TIRF REMS Program

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MS, University of Chicago, 2003
MD, Case Western Reserve University, 1998
BA, University of Pennsylvania, 1993


Dr. Alexander is a Professor of Epidemiology and Medicine at the Johns Hopkins Bloomberg School of Public Health, where he serves as founding co-Director of the Center for Drug Safety and Effectiveness and Principal Investigator of the Johns Hopkins-FDA Center of Excellence in Regulatory Science and Innovation (JH-CERSI). He is a practicing general internist and pharmacoepidemiologist and is internationally recognized for his research examining prescription drug utilization, safety and effectiveness. The author of over 275 scientific articles and book chapters, and he has published regularly in leading scientific journals, serves on several editorial and advisory boards and is a frequent speaker on pharmaceutical utilization and policy. In addition to expertise conducting survey-based investigations, Dr. Alexander also has extensive experience with the analysis of secondary data sources including administrative and pharmacy claims and large national surveys. Dr. Alexander received his B.A. cum laude from the University of Pennsylvania, an MD from Case Western Reserve University, and a Master of Science from the University of Chicago.

Research Interests: prescription drugs; drug utilization; drug safety; drug effectiveness; pharmacoepidemiology; pharmaceutical policy

Honors and Awards


1993 Cum Laude, University of Pennsylvania

1997 Alpha Omega Alpha, Case Western Reserve University

2011 Elected Fellow of the American College of Physicians (FACP)



2001 Edward W. Holmes Resident Research Award, University of Pennsylvania

2006-2009  Robert Wood Johnson Foundation Faculty Scholar

2007 Research Finalist, International Society for Pharmacoeconomics and Outcomes Research, Annual Meeting

2008 Outstanding Physician Scientist Award, Central Society for Clinical Research

2008 Career development award, Central Society for Clinical Research

2008 Department of Medicine Research Award (awarded to trainee for mentored research; also received by mentored trainees in 2009 and 2010)

2009 Pritzker School of Medicine Sigma Xi Award for Impact on Science (awarded to trainee for mentored research)

  • prescription drugs
  • drug utilization
  • drug safety
  • drug effectiveness
  • patient-provider communication
  • pharmacoepidemiology
  • regulatory policy
  • Food and Drug Administration

Select Scientific Publications (of over 275 total)

  • Alexander GC, Frattaroli S, Gielen AC, eds. The Opioid Epidemic: From Evidence to Impact. Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland: 2017.
  • Kolodny A, Courtwright DT, Hwang CS, Kreiner P, Eadie JL, Clark TW, Alexander GC. The Prescription Drug Opioid and Heroin Crisis: A Public Health Approach to an Epidemic of Addiction. Annual Review of Public Health. 2015;36:559-574.
  • Qato DM, Wilder J, Schumm P, Gillet V, Orr A, Alexander GC. Use of Prescription and Over-the-counter Medications and Dietary Supplements Among Older Adults in the United States: 2005-2006 to 2010-2011. JAMA Internal Medicine. 2016;176:473-82.
  • Yin W, Basu A, Zhang J, Rabbani A, Meltzer DO, Alexander GC. Impact of the Medicare Part D Prescription Drug Benefit on Drug Utilization and Out-of-pocket Expenditures. Annals of Internal Medicine. 2008;148:169-177.
  • Dusetzina SB, Higashi A (*co-first author), Dorsey ER, Conti R, Huskamp HA, Zhu S, Garfield CF, Alexander GC. Impact of FDA risk communications on health care utilization and health behaviors: a systematic review. Medical Care. 2012;50:466-78