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Hsien-Yen Chang, PhD

  • Associate Scientist

Departmental Affiliations

Center & Institute Affiliations

Contact Information

624 N. Broadway
Hampton House 682
Baltimore, Maryland 21205


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Publons (Reviewer Record)

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PhD, Johns Hopkins Bloomberg School of Public Health, 2008
MHS, Johns Hopkins Bloomberg School of Public Health, 2006
MS, Harvard School of Public Health, 2003
MS, National Yang-Ming University, 1997
BS, National Taiwan University, 1995


Risk adjustment and its applications


Opioid abuse

Overuse measurements and their applications

Outcome evaluation and cost-effectiveness analysis

Honors and Awards

Phi Beta Kappa Honor Society, 2009-Present                     

Taiwan Merits Scholarships, 2005–2008                               

Rotary Foundation Academic-Year Ambassadorial Scholar, 2001–2002

  • Risk Adjustment
  • Drug Safety
  • Pharmacoepidemiology
  • Opioid abuse
  • Health services research

Selected publications from the last two years.

  • Chang HY, Singh S, Mansour O, et al. Association Between Sodium-Glucose Cotransporter 2 Inhibitors and Lower Extremity Amputation Among Patients With Type 2 Diabetes. JAMA Intern Med. 2018;178(9):1190-1198.
  • Chang HY, Kharrazi H, Bodycombe D, et al. Healthcare costs and utilization associated with high-risk prescription opioid use. BMC Medicine. 2018:16:69.
  • Chang HY, Murimi I, Mark F, et al. Impact of prescription drug monitoring programs and pill mill laws on high-risk patients. Pharmacoepidemiol Drug Saf. 2018 Apr;27(4):422-429.
  • Chang HY, Murimi I, Jones C, Alexander GC. Relationship Between High-Risk Patients Receiving Prescription Opioids and High-Volume Opioid Prescribers. Addiction. 2018 Apr;113(5):677-686
  • Chang HY, Richards TM, Shermock KM, et al. Evaluating the Impact of Prescription Fill Rates on Risk Stratification Model Performance. Med Care. 2017 Dec;55(12):1052-1060.