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Adam P. Spira, PhD

  • Associate Professor

Departmental Affiliations

Contact Information

624 N. Broadway
Hampton House 794
Baltimore, Maryland 21205


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PhD, West Virginia University, 2004
MA, West Virginia University, 2001
BA, State University of New York at Stony Brook, 1998


My research is focused on understanding the association of sleep disturbances and psychopathology with cognitive and functional outcomes in later life, and particularly with the development of Alzheimer's disease. The ultimate goal is to use this knowledge to develop interventions to curb the burden of Alzheimer's disease, and more generally improve cognitive and functional trajectories.

Honors and Awards

Fellow, Gerontological Society of America, Behavioral and Social Sciences Section, May 2015

Insomnia Section Investigator Award, American Academy of Sleep Medicine, June 2013

Advising, Mentoring, and Teaching Recognition Award (AMTRA), Johns Hopkins Bloomberg School of Public Health Student Assembly, May 2013

Barry Lebowitz Early Career Scientist Award, American Association for Geriatric Psychiatry, March 2013

International Junior Investigator Award, International College of Geriatric Psychoneuropharmacology, June 2009

JHSPH Faculty Innovation Fund Award, 2009-2010

Licensed psychologist in Maryland (# 04619, expires 03/31/2017)

Admitted to National Institutes of Health Loan Repayment Program, July 2007

Completed National Institute of Mental Health Summer Research Institute in Geriatric Psychiatry, July 2005

Association for Advancement of Behavior Therapy, Behavior Therapy and Aging Special Interest Group Poster Award, November 2004

Higher Education Research Fund Fellowship, West Virginia University, 2002, 1999

Phi Beta Kappa Honor Society, State University of New York at Stony Brook, June 1998

  • Aging, sleep disturbances, anxiety, depression, Alzheimer's disease, cognitive decline, functional decline

Selected publications from the last five years:

  • Spira, A. P., An, Y., Peng, Y., Wu, M. N., Simonsick, E. M., Ferrucci, L., & Resnick, S. M. (2017). APOE genotype and non-respiratory sleep parameters in cognitively intact older adults. SLEEP, May 6, Epub ahead of print.
  • Spira, A. P., Stone, K. L., Redline, S., Ensrud, K. E., Ancoli-Israel, S., Cauley, J. A., & Yaffe, K. (2017). Sleep duration and fragmentation in older women: Associations with performance across cognitive domains. SLEEP, May 2, Epub ahead of print.
  • Spira, A. P., Gonzalez, C. E., Venkatraman, V., Wu, M. N., Pacheco, J., Simonsick, E. M., Ferrucci, L., & Resnick, S. M. (2016). Sleep duration and subsequent cortical thinning in cognitively normal older adults. SLEEP, 39(5), 1121-8.
  • Spira, A. P., Stone, K., Rebok, G. W., Punjabi, N., Redline, S., Ancoli-Israel, S. & Yaffe, K. (2014). Sleep-disordered breathing and functional decline in older women. Journal of the American Geriatrics Society, 62, 2040-2046.
  • Spira, A. P., Gamaldo, A. A., An, Y., Wu, M. N., Simonsick, E. M., Bilgel, M., Zhou, Y., Wong, D. F., Ferrucci, L., & Resnick, S. M. (2013). Self-reported sleep and beta-amyloid deposition in community-dwelling older adults. JAMA Neurology, 70(12), 1537-1543.
  • Actigraphic Assessment of Sleep Quality in the A4 Trial (R01AG049872; MPIs: P. B. Rosenberg & A. P. Spira)
  • Poor Sleep Altered Circadian Rhythms and Alzheimers Disease (R01AG050507; PI: Spira)
  • Stress, Mental Disorders, Accelerated Aging, and Dementia: a 35-year Cohort Study (U01AG052445; MPIs: A. P. Spira & W. W. Eaton)
  • The ARIC Study of Midlife Sleep and Late-Life Brain Amyloid (RF1AG050745; MPIs: A. P. Spira & R. F. Gottesman)