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Qian-Li Xue, PhD

  • Associate Professor

Departmental Affiliations

Contact Information

2024 E. Monument Street
Suite 2-700
Baltimore, Maryland


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My primary area of statistical expertise is the development and application of statistical methods for (i) handling truncation of information on underlying or unobservable outcomes (e.g., disability) as a result of screening, (ii) missing data including outcome (e.g. frailty) censoring by a competing risk (e.g. mortality), and (iii) trajectory analysis of multivariate outcomes. Other areas of methodologic research interests include multivariate, latent variable models.

In Women's Health and Aging Studies, I have closely collaborated with scientific investigators on the design and analysis of longitudinal data relating biomarkers of inflammation, hormonal dysregulation, and micronutrient deficiencies to the development and progression of frailty and disability, as well as characterizing the natural history of change in cognitive and physical function over time.

Honors and Awards

2000 Student Paper Award from the International Biometrics Society Eastern North American Region

2007 Travel Award, Conference on Biomarkers of Aging, American Federation of Aging Research

2010-2011 Nathan Shock Scholar, the Nathan W. and Margaret T. Shock Aging Research Foundation

  • Epidemiology,Epidemiological design
  • latent variable
  • longitudinal data
  • measurement error
  • missing data
  • multivariate categorical data

Selected publications from the last five years

  • Xue QL, Guralnik JM, Beamer BA, Fried LP, Chaves PHM. Monitoring six-month trajectory of grip strength improves the prediction of long-term change in grip strength in disabled older women. J Gerontol A Biol Sci Med Sci. 2014 Aug 28. pii: glu149. [Epub ahead of print] PMID: 25167868
  • Xue QL, Bandeen-Roche K, Mielenz, TJ, Seplaki CL, Szanton SL, Thorpe RJ, Kalyani RR, Chaves PH, Dam TT, Ornstein K, RoyChoudhury A, Varadhan R, Yao WL, Fried LP. Patterns of 12-Year Change in Physical Activity in Community-Dwelling Older Women: Can Modest Levels of Physical Activity Help Older Women Live Longer? Am J Epidemiol. 2012 Sep 15;176(6):534-43. PMID:22935515
  • Krall JR, Carlson MC, Fried LP, Xue QL. Examining the dynamic, bidirectional associations between cognitive and physical functions. Am J Epidemiol. 2014 Sep 8. pii: kwu198. [Epub ahead of print] PMID: 25205829
  • Xue QL, Beamer BA, Chaves PHM, Guralnik JM, Fried LP. Heterogeneity in rate of decline in grip, hip, and knee strength and the risk of all-cause mortality: The Women’s Health and Aging Study II. J Am Geriatr Soc. 2010 Nov;58(11):2076-84. PMID: 21054287
  • Xue QL, Fried LP, Glass TA, Laffan AM, Chaves PHM. Life-space constriction, development of frailty, and the competing risk of mortality: The Women’s Health and Aging Study I. Am J Epidemiol. 2008; 167(2):240-48. PMID: 17906296