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W. Harry Feinstone Department of Molecular Microbiology and Immunology

Centers and Institutes

Johns Hopkins Malaria Research Institute

The Johns Hopkins Malaria Research Institute comprises several research groups that study different aspects of malaria, ranging from mosquito population biology to vaccine and drug research, at the basic and translational level. The institute comprises state-of-the-art core facilities and a field laboratoiry in Macha, Southern Zambia. It also provides research support through pilot grant and fellowship support.

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R3 Center for Innovation in Science Education (R3ISE)

R3 Center for Innovation in Science Education

Innovation in science must include education. The R3 Center for Innovation in Science Education (R3ISE) forms a focal point for innovation in scientific training at the Johns Hopkins Bloomberg School of Public Health. At its core are the 3 R's of good scientific practice: Rigor, Responsibility and Reproducibility.
In the early 20th century, Johns Hopkins provided the academic model that led to modern medicine. Now in the early 21st century, the R3 Center for Innovation in Science Education will position the Johns Hopkins Bloomberg School of Public Health, to catalyze the improvement of graduate scientific education.

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Multicenter AIDS Cohort Study (MACS) / Study to Help the AIDS Research Effort (SHARE)macs-2

SHARE, the Study to Help the AIDS Research Effort, is one of four clinical sites of the Multicenter AIDS Cohort Study (MACS). The other sites are located in Los Angeles, Chicago, and Pittsburgh. The sites were funded in 1983 by the National Institute of Allergy and Infectious Diseases (NIAID) to investigate the natural history of a new infection, that came to be known as HIV/AIDS. In 1987, the Center for the Analysis and Management of MACS data (CAMACS) was established at the Johns Hopkins Bloomberg School of Public Health. The study seeks to: Characterize the range of responses to HAART (Highly Active Antiretroviral Therapy), with special emphasis on the disease stage at which HAART is taken; Define the effect of HAART on clinical outcomes i.e., AIDS, infections, etc. ; Compare clinical outcomes in people who receive HAART and those who do not; Characterize the long-term adverse effects and treatment-related effects of HAART; Describe long-term patterns of HAART use; Ascertain long-term patterns of behavior that can lead to the spread of HIV infection.

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Johns Hopkins Center of Excellence in Influenza Research and Surveillance (JH CEIRS)jh-ceirs

The National Institute of Allergy and Infectious Diseases (NIAID) Centers of Excellence for Influenza Research and Surveillance (CEIRS) program is an integrated network of centers designed to bring together multidisciplinary teams of researchers that perform surveillance related research integrated with research on host immune response, viral pathogenesis, and the factors that control the emergence and transmission of influenza viruses. The JH CEIRS performs human influenza surveillance in the United States, Taiwan and Zambia with an overall goal of increasing our understanding of how seasonal influenza circulates in the human population and to provide the information and public health tools needed to control the impact of epidemic and pandemic influenza.

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Specialized Center of Research Excellence (SCORE) in Sex and Age Differences in immunity to influenza (SADII)

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Despite having antivirals and vaccines, influenza remains a significant public health threat, and sex and age are emerging as two host variables that significantly impact the pathogenesis of influenza virus infection and responses to influenza vaccines. The Sex and Age Differences in Immunity to Influenza (SADII) SCORE is leveraging the internationally recognized research, resources, and educational opportunities at Johns Hopkins University to transform women’s health and impact the development of and policy decisions about influenza vaccine programs, including universal influenza vaccines. Through novel collaborations, career enhancement of diverse clinicians and scientists, and use of translational research approaches, we are positioned to transform our understanding of the role of biological sex, gender, and aging on immune responses to influenza vaccination, which has global public health implications, affecting millions of people worldwide.

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