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Population, Family and Reproductive Health

Research

Antihypertensive Medication in Pregnancy: An Update from the 2011 WHO Recommendations for Prevention and Treatment of Preeclampsia and Eclampsia

Donna Strobino, Saifuddin Ahmed, Erika Werner (Brown Univ, school of Medicine), Mahua Mandal, Laina Gagliardi, and Roxanne Beltran
The aim of this project is to update the science behind WHO recommended anti-hypertensive medications in pregnancy to prevent preeclampsia and manage hypertension and to estimates the prevalence of chronic hypertension, preeclampsia and all hypertensive disorders in pregnancy using data from population- based studies worldwide and facility based studies in resource poor settings. The study also using extant data to estimate unmet need and potential demand for antihypertensive medications in pregnancy in low resource settings.

Contraceptive Efficacy of a Novel Vaginal Ring

Anne Burke
This is an upcoming NICHD-funded, prospective study evaluating use of a vaginal contraceptive ring in healthy women. Pharmacokinetics of oral contraceptives before and after bariatric surgery. This study compares pharmacokinetic and pharmacodynamic profiles of oral contraceptive use for women undergoing gastric bypass surgery. 

Developing and Piloting A Gender-Based Violence Intervention Module to Reduce HIV Risk among Female Sex Workers (FSWs)

Michele Decker, Susan Sherman (Epi), Nancy Glass (School of Nursing)
With support from the Johns Hopkins Center for AIDS Research (P30AI094189, PI Chaisson), this initiative uses a community-based participatory approach to develop and pilot test a brief violence intervention module to encourage violence-related harm reduction, provide social support related to violence victimization, and reduce related HIV risk behavior among women who trade sex or are sexually exploited.

Duration of Hormonal Contraceptive Use: Immune Responses & Vaginal Microbiota

PI: Dr. Khalil Ghanem – Co-investigator: Anne Burke
This NIH-funded study investigates the impact of hormonal contraceptives on the vaginal microbiome.
Use of postpartum IUDs and implants. This study evaluates outcomes in women who receive long-acting contraception in the immediate postpartum period.

Gendered Risk, Substance Use and HIV among Urban Women

Michele Decker, Susan Sherman (Epi), Elizabeth Golub (Epi)
With support from NIDA (R03DA035691), this study harnesses the Women’s Interagency HIV Study (WIHS), the largest and longest-running HIV cohort study of women in the US, to describe constellations of gendered risk, and evaluate their influence on substance use trends and behavioral and biologic HIV outcomes among marginalized urban women.

Social-Structural Determinants of Young Women’s Reproductive Health

Michele Decker, Michelle Hindin
This collaboration with World Health Organization entails review and analysis of population-level indicators of economic well-being, inequality and gender equity as they relate to women’s health indicators include early birth and family planning use, and trends therein, in low and middle income countries.

Strengthening the Health Sector to Reduce Reproductive Coercion and Intimate Partner Violence

Michele Decker in collaboration with Children’s Hospital of Pittsburgh
With support from NICHD (1R01HD064407), this cluster RCT evaluates a family planning clinic-based intervention to facilitate help-seeking, reduce intimate partner violence victimization and reproductive coercion, increase use of long-acting reversible contraception, and prevent unintended pregnancy.

Well-being of Adolescents in Vulnerable Environments (WAVE)

Bob Blum, Michele Decker, Beth Marshall, Kristin Mmari, Freya Sonenstein
This mixed methods study sought to understand the health concerns and challenges to health among a cross-national sample of adolescents.   We conducted extensive qualitative research followed by a cross-sectional quantitative survey with youth recruited via respondent-driven sampling (RDS), with data collection in South Africa, India, China, Nigeria and the United States.