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Graduate Summer Institute of Epidemiology and Biostatistics

Public Health Dimensions of Global Tuberculosis Control: New Tools and Interventions

2 credits

Course Number: 340.681.11


Course Instructors:

·     Jaap Broekmans
·     Jonathan Golub


Systematically reviews the foundations of tuberculosis control in both TB high burden and industrialized countries with special emphasis on the introduction of new tools and evidence-based interventions. Critically examines new TB diagnostics (GeneXpert MTB/RIF), new TB drugs (shorter regimens for drug-sensitive and drug resistant tuberculosis), the evidence base of TB-HIV interventions and the rationale for systematic screening for active tuberculosis. Explains the rationale of the new post-2015 global TB strategy and targets. Defines the global TB disease burden and the status of the global response. Reviews the role of WHO, Global Fund to fight AIDS Tuberculosis and Malaria (GFATM), Stop TB Partnership, Bill and Melinda Gates Foundation and USAID. Case studies and concrete examples are derived from the experience in TB high burden countries (Brazil, South-Africa, Tanzania, Vietnam, Indonesia, China) and in industrialized countries (The Netherlands and USA). Students analyze and present important publications from the TB literature in the Comstock exercise.

Student Evaluation: Group Project

Learning Objectives:

Grading Options: Letter Grade or Pass/Fail

Course Materials: Provided in class and through CoursePlus