223.690.01
The Design and Analysis of Cluster Randomized Trials
- Location:
- East Baltimore
- Term:
- 4th term
- Department:
- International Health
- Credits:
- 2 credits
- Academic Year:
- 2022 - 2023
- Instruction Method:
- In-person
- Class Times:
-
- Tuesday, 3:30 - 5:20pm
- Auditors Allowed:
- Yes, with instructor consent
- Undergrads Allowed:
- No
- Grading Restriction:
- Letter Grade or Pass/Fail
- Course Instructor:
- Contact:
- Aletta Nonyane
- Resources:
- Prerequisite:
Biostatistics 621, 622, 623, 624 or equivalent sequence.
- Description:
-
Covers the major concepts and methods in the design and analysis of trial in which the unit of randomization is a group of participants. Focuses on design: discusses unmatched, matched, stepped wedge, and other approaches, with particular attention paid to randomization and sample size considerations. Presents a variety of methods for the analysis of these correlated-outcomes studies. Includes special aspects of infectious disease interventions.
- Learning Objectives:
-
Upon successfully completing this course, students will be able to:
- Identify when a cluster randomized trial may be preferable to an individually randomized trial
- Determine optimal design strategies for enabling estimation of efficacy and effectiveness parameters of interest
- Conduct and interpret statistical analyses appropriate to these designs
- Methods of Assessment:
This course is evaluated as follows:
- 60% Weekly exercises
- 40% Short project paper outlining a new trial with critical features and options discussed
- Instructor Consent:
No consent required