415.866.92
Current Topics in Molecular Genetics I
- Location:
- NIH - Bethesda, MD
- Term:
- 3rd term
- Department:
- Health Behavior and Society
- Credits:
- 1 credits
- Academic Year:
- 2022 - 2023
- Instruction Method:
- TBD
- Class Times:
-
- Wednesday, 4:00 - 4:50pm
- Auditors Allowed:
- Yes, with instructor consent
- Undergrads Allowed:
- No
- Grading Restriction:
- Letter Grade or Pass/Fail
- Course Instructor:
-
- Ellen Macnamara
- Contact:
- Lori Erby
- Resources:
- Prerequisite:
415.610-.613; Must be enrolled in ScM in Genetic Counseling Program
- Description:
-
Provides a review of molecular diagnosis of common hereditary or neoplastic disorders for which DNA-based diagnosis is now in routine use, including FGFR3 disorders, fetal blood typing, thrombophilias, hemochromatosis, fragile X syndrome, polyglutamine disorders, hereditary breast cancers, Charcot Marie Tooth and spinal muscular atrophy, Prader Willi and Angelman syndromes, mitochondrial diseases, Duchenne and Becker muscular dystrophy, cystic fibrosis, and Smith-Lemli-Opitz Syndrome. Includes instruction in genetic risk prediction, using linkage and Bayesian analysis as well as DNA forensics and paternity testing.
- Learning Objectives:
-
Upon successfully completing this course, students will be able to:
- Describe the types of techniques used in molecular genetic diagnostic laboratories, including the limitations of each assay
- Calculate residual risks after molecular testing
- Discuss how to interpret molecular genetic results
- Methods of Assessment:
Two oral presentations (50%) and class participation (50%)
- Multiterm:
Final grade applies to all terms
- Instructor Consent:
No consent required
- Special Comments:
Students must register for both 3rd and 4th term.