330.651.79
How to Derive a Polygenic Risk Score
Course Status
Cancelled
Course Status
Cancelled
Location
Internet
Term
Summer Institute
Department
Mental Health
Credit(s)
2
Academic Year
2022 - 2023
Instruction Method
Synchronous Online
Start Date
Monday, June 13, 2022
End Date
Thursday, June 16, 2022
M, Tu, W, Th, 8:30am - 12:20pm
Auditors Allowed
No
Available to Undergraduate
No
Grading Restriction
Letter Grade or Pass/Fail
Course Instructor(s)
Contact Name
Frequency Schedule
One Year Only
Resources
Do you plan to use genetic risk scores in your data? Do you need to know how to derive and analyze these scores using state-of-the art methods. This course will give you the tools you need to make polygenic scores from your own genotype data, while drawing on examples from mental health.
Explores what polygenic risk scores are, and what they have revealed to date about human genetic mental health outcomes, with computer laboratory exercises to step-by-step develop the tools needed to create and analyze these scores with genetic study data. Includes creating summary statistics and descriptive figures.
Learning Objectives
Upon successfully completing this course, students will be able to:
- Define and explain what is a polygenic risk score
- Code a polygenic risk score in a target genetic dataset
- Analyze and create figures to display the behavior of a polygenic risk score in target data
- Describe what information the polygenic risk scores has provided to the research community about several common health outcomes
Methods of Assessment
This course is evaluated as follows:
- 60% Lab Assignments
- 40% Final Exam