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Statistical Methods in Public Health II


East Baltimore
2nd term
4 credits
Academic Year:
2022 - 2023
Instruction Method:
Class Times:
  • Tu Th,  10:30 - 11:50am
Auditors Allowed:
Yes, with instructor consent
Undergrads Allowed:
Grading Restriction:
Letter Grade or Pass/Fail
Course Instructors:
Karen Bandeen-Roche



Presents use of confidence intervals and and hypothesis tests to draw scientific statistical inferences from public health data. Introduces generalized linear models, including linear regression and logististic regression models. Develops unadjusted analyses and analyses adjusted for possible confounders. Outlines methods for model building, fitting and checking assumptions. Focuses on the accurate statement of the scientific question, appropriate choice of generalized linear model, and correct interpretation of the estimated regression coefficients and confidence intervals to address the question.

Learning Objectives:

Upon successfully completing this course, students will be able to:

  1. Use statistical reasoning to formulate public health questions in quantitative terms
  2. Distinguish between the appropriate generalized linear regression models for expressing the relationship between a response (dependent variable or outcome) and one or more independent variables
  3. Recognize the assumptions required in using regression models and performing statistical tests to assess relationships between an outcome and a risk factor
  4. Use statistical methods for inference, including confidence intervals and tests, to draw valid public health inferences from study data
  5. Formulate and correctly interpret relationships in a linear regression model.
  6. Interpret the correlation coefficient as a measure of the strength of a linear association between a continuous response variable and a continuous predictor variable
  7. Interpret the coefficients, including interaction coefficients, obtained from a multiple linear regression analysis
  8. Estimate a confidence interval for a linear regression coefficient; interpret the interval estimates within a scientific context
  9. Distinguish the summary measures of association applicable to retrospective and prospective study designs
  10. Estimate two proportions and their difference, and confidence intervals for each; interpret the interval estimates within a scientific context
  11. Estimate an odds ratio, or relative risk, and its associated confidence interval; explain the difference between the two and when each is appropriate
  12. Interpret the coefficients, including interaction coefficients, obtained from a multiple logistic regression analysis
  13. Assess whether the relationship between a response (dependent) variable and an independent variable varies by the level of a second independent variable (effect modification)
  14. Recognize the influence of sample size on statistical inferences
  15. Use the Stata statistical analysis or R packages to perform regression analyses
Methods of Assessment:

This course is evaluated as follows:

  • 20% Assessments
  • 10% Quizzes
  • 70% Exam(s)

Enrollment Restriction:

For PhD, ScM and MHS degree candidates in departments to be determined

Instructor Consent:

Consent required for some students

Consent Note:

Consent required for non-PH students

For consent, contact:

Special Comments:

Registration is expected to open for this section on or about October 5, 2020.