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Biological Response to Biomaterials


East Baltimore
4th term
Molecular Microbiology and Immunology
3 credits
Academic Year:
2021 - 2022
Instruction Method:
Class Times:
  • Tu Th,  3:30 - 4:50pm
Auditors Allowed:
Yes, with instructor consent
Grading Restriction:
Letter Grade or Pass/Fail
Course Instructor:
  • Carmelita Frondoza
Carmelita Frondoza

Focuses on the clinical applications of biomaterials as medical devices: (1) to repair, replace organs and tissues; and (2) to deliver drugs, growth factors and other agents to stimulate, enhance, and restore function. Covers biomaterials used in clinical settings such as orthopedics, cardiovascular, dental, neurological and reconstructive/cosmetic surgery. Discusses chemical, physical and mechanical properties of currently used, new and novel biomaterials being developed that determine success or failure. Identify biological responses (immune and non-immune) that determine the fate of biomaterial medical devices. Provides state of the art information on public health concerns with respect to the use of biomaterials in medicine.

Learning Objectives:

Upon successfully completing this course, students will be able to:

  1. Identify biomaterials used for tissue regeneration, repair, or replacement and as delivery systems for restoration of function
  2. Explain tissue, organ, system response (non-immune, immune) to biomaterial medical devices
  3. Discuss regulatory issues for public health safety with the use of standard and new biomaterial compositions and combination devices
Methods of Assessment:

This course is evaluated as follows:

  • 10% Participation
  • 20% Midterms, abstract write up
  • 70% Finals, presentation & paper write up

Instructor Consent:

No consent required