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Alternative Methods in Animal Testing

4th term
Environmental Health and Engineering
3 credits
Academic Year:
2021 - 2022
Instruction Method:
Asynchronous Online with Some Synchronous Online
Auditors Allowed:
Yes, with instructor consent
Grading Restriction:
Letter Grade or Pass/Fail
Course Instructor:
Joseph Bressler

Introduction to Online Learning is required prior to participating in any of the School's Internet-based courses.


Discusses and evaluates strategies for reducing the number of animals utilized in basic and applied research. Addresses traditional in vitro methods, including cell culture and analytical chemistry as well as newer and evolving techniques such as informatics, genomics, proteomics, and metabolomics. Also discusses governmental regulatory processes for approving new testing methods, especially in vitro methods.

Learning Objectives:

Upon successfully completing this course, students will be able to:

  1. Identify concerns in designing in vitro methods used to replace or supplement in vivo methods
  2. Evaluate tissue culture methods for their ability to provide useful data
  3. Define the strengths and limitations of bioinformatic techniques for reducing the numbers of animals in applied basic research
  4. Explain the regulatory process in approving, verifying, and validating in vitro methods
Methods of Assessment:

This course is evaluated as follows:

  • 50% Midterm
  • 50% Final Exam

Enrollment Restriction:

Enrollment restricted to students in the MS degree program or the Humane Sciences and Toxicology certificate program

Instructor Consent:

No consent required