Stem Cells and the Biology of Aging and Disease
- East Baltimore
- 3rd term
- Biochemistry and Molecular Biology
- 3 credits
- Academic Year:
- 2021 - 2022
- Instruction Method:
- Synchronous Online
- Class Times:
Classes are recorded and can be viewed at a later time. Class attendance at the specific time is not mandatory.
- M W, 10:30 - 11:50am
Course in biochemistry, molecular biology, or cell biology at undergraduate or graduate level.
Exposes students to cutting-edge topics in stem cell biology through a combination of lectures and discussions based on primary literature. Topics include basic stem cell biology in a invertebrate and vertebrate systems, including germline, neural, and Leydig stem cells; the regulation of stem cells by physiology and aging; the connection between stem cells, telomerase, and cancer; and ethical issues pertaining to potential therapeutic applications of stem cells.
- Learning Objectives:
- Explain some of the basic cellular and molecular mechanisms that ensure self-renewal of stem cells
- Compare and contrast the regulation and function of stem cells in different systems
- Explain how physiology and aging impacts stem cell behavior and function
- Discuss how telomerase function is relevant to stem cells and cancers
- Raise some of the ethical issues in stem cell research and its therapeutic applications.
- Methods of Assessment:
This course is evaluated as follows:
- 45% Midterm
- 45% Final Exam
- 10% Participation
- Instructor Consent:
No consent required