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Seminar On Aging, Cognition and Neurodegenerative Disorders


East Baltimore
2nd term
Mental Health
2 credits
Academic Year:
2021 - 2022
Instruction Method:
Class Times:
  • Thursday,  3:30 - 5:20pm
Auditors Allowed:
Yes, with instructor consent
Grading Restriction:
Course Instructors:
George Rebok
Frequency Schedule:
Every Other Year

Addresses age-related cognitive and neuropsychiatric disorders that are of particular importance with the rapid expansion of the aging population. Focuses on the major domains of cognition and comparison of the age-related changes that occur in each cognitive domain. Includes emphasis on contrasting the major neurodegenerative disorders related to age and describing the clinical presentation and pattern of cognitive change in each condition. Addresses current strategies for maximizing cognitive function with age and treatment strategies for the primary neurodegenerative disorders. Examines and identifies gaps in knowledge and research approaches to fill these gaps. Explores concepts of cognitive systems, animal and imaging models, and neuropathological changes associated with aging and with disease.

Learning Objectives:

Upon successfully completing this course, students will be able to:

  1. Discuss age-related cognitive change in cognition in animal models
  2. Discuss age-related cognitive change in major cognitive domains across the age range
  3. Identify challenges of screening older persons for cognitive impairment
  4. Review statistical challenges associated with clinical trials in older persons
  5. Discuss approaches to modifying age-related cognitive declines
Methods of Assessment:

Class participation 30%; term paper 70%

Instructor Consent:

Consent required for all students

Consent Note:
For consent, contact:

Special Comments:

Predoctoral and Postdoctoral students from A&S, SPH and Medicine students participating in training grant on age-related, cognitive and neuropsychiatric disorders.