260.611.01
Principles of Immunology I
Cancelled
- Location:
- East Baltimore
- Term:
- 1st term
- Department:
- Molecular Microbiology and Immunology
- Credits:
- 4 credits
- Academic Year:
- 2021 - 2022
- Instruction Method:
- TBD
- Class Times:
-
- Tu Th, 8:30 - 10:20am
- Auditors Allowed:
- Yes, with instructor consent
- Grading Restriction:
- Letter Grade or Pass/Fail
- Course Instructor:
- Contact:
- Alan Scott
- Resources:
- Prerequisite:
A course in advanced biology
- Description:
-
Introduces biological concepts of immunology; molecular nature of antigens; molecular basis for antibody and T-cell receptor structure and diversity; complement; hypersensitivity reactions; cellular basis for the immune response; cell-mediated immunity; adhesion molecules and coreceptors cell activation; cytokines and other soluble mediators; major histocompatibility complex (MHC) antigens; tumor immunology; transplantation immunobiology; mechanisms of resistance to microorganisms; tolerance; autoimmunity; and immuno-deficiency.
- Learning Objectives:
-
Upon successfully completing this course, students will be able to:
- Define the tissue, cellular and molecular components that constitute the vertebrate innate and adaptive immune system
- Explain the generation of lymphocyte antigen receptors and the molecular and cellular basis for diversity and specificity of receptors on immune cells
- Define the basis for antigen presentation to T cells
- Define the basis for recognition of self and non-self recognition
- Define the development and survival of lymphocytes
- Explain the major signaling pathways used by immune cells
- Define T cell-mediated and B cell-mediated immunity
- Methods of Assessment:
Student evaluation based on mid-term and final exams.
- Instructor Consent:
Consent required for some students
- Consent Note:
Consent is required for undergraduate students.
- For consent, contact:
- Special Comments:
Required for MMI PhD students.