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Biology of Parasitism

East Baltimore
2nd term
Molecular Microbiology and Immunology
5 credits
Academic Year:
2021 - 2022
Instruction Method:
Class Times:
First and Third Tuesday, 12:00-1:20pm
  • M W F,  1:30 - 2:20pm
Lab Times:
  • M W F,  2:30 - 3:20pm
    Held in wet lab after lecture
Auditors Allowed:
Yes, with instructor consent
Grading Restriction:
Letter Grade or Pass/Fail
Course Instructors:
David Sullivan

Presents a biological basis of parasitic lifestyles including host responses and parasite evasion of host defense mechanisms, transmission, epidemiology, diagnosis, clinical manifestations, pathology, treatment, and control of the major helminthic and protozoan infections of man

Learning Objectives:

Upon successfully completing this course, students will be able to:

  1. Discuss the biological and genetic bases for host-parasite adaptation
  2. Define the scope of parasitic infections of global public health importance
  3. Explain epidemiological concepts of relevance to parasite infections, including ecological relationships between humans, vectors, and reservoirs of parasitic diseases
  4. Explain the methods of diagnosis, identification and detection of parasites
  5. Describe the pathological changes associated with parasite infections
  6. Discuss the role of vectors and intermediate hosts in parasite transmission considering the concept of One Health
  7. Explain the role of vertebrate innate and adaptive immune system in controlling parasites
  8. Describe molecular biology concepts unique to parasite infections
  9. Define the biochemical targets for drugs targeting parasites
  10. Define the mechanisms of drug resistance
  11. Define the immune evasion strategy employed by certain parasites
Methods of Assessment:

This course is evaluated as follows:

  • 50% Midterm
  • 50% Final Exam

Instructor Consent:

No consent required

Special Comments:

Required for MMI PhD students. MMI ScM and MHS students may opt to count this course towards their requirements. Laboratory sessions examine living and preserved parasites, gross pathology, histopathology, and vectors. Journal discussions based on research papers and topics of fundamental importance to parasitology involve student participation in a seminar format.