187.640.01
Toxicology 21: Scientific Foundations

Location
East Baltimore
Note: Due to the COVID-19 Pandemic, this course was held in a virtual/online format.
Term
2nd Term
Department
Environmental Health and Engineering
Credit(s)
1
Academic Year
2020 - 2021
Instruction Method
TBD
Class Time(s)
Wednesday, 3:30 - 4:20pm
Auditors Allowed
No
Available to Undergraduate
No
Grading Restriction
Letter Grade or Pass/Fail
Course Instructor(s)
Joseph Bressler
Contact Name
Joseph Bressler
Frequency Schedule
Every Year
Prerequisite

187.610 Public Health Toxicology

Description
Provides students with fundamental knowledge of the emerging science driving new strategies for human risk assessment. Topics include toxicokinetics, xenobiotic activation and inactivation, systems biology, and databases for toxicity testing. Presents case studies that have used different data bases for toxicity testing. Students have hands-on experiences using the databases and other Web-based applications.
Learning Objectives
Upon successfully completing this course, students will be able to:
  1. Discuss the metabolism of xenobiotics
  2. Apply the principles of xenobiotic metabolism and drug-drug interaction to pharmacokinetics and toxicokinetics
  3. Explain the basis of differences in xenobiotic metabolism in different populations
  4. Analyze the scientific evidence for the development of new toxicity testing strategies
Methods of Assessment
This course is evaluated as follows:
  • 50% Exam(s)
  • 30% Assignments
  • 20% Participation
Instructor Consent
Consent required for some students
Consent Note
Consent required for students not in the MS in Toxicology for Human Risk Assessment, MHS, or ScM in Environmental Health THRA area of focus
Consent Contact
jbressl1@jhu.edu
Special Comments

Students in the MS in Toxicology for Human Risk Assessment, MHS, or ScM in Environmental Health THRA area of focus must take 187.632 Molecular Toxicology concurrently.

Course will be held in departmental space.