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Course Catalog

187.633.01 Introduction to Environmental Genomics and Epigenomics

Department:
Environmental Health and Engineering
Term:
4th term
Credits:
3 credits
Academic Year:
2019 - 2020
Location:
East Baltimore
Class Times:
  • W F,  3:30 - 4:50pm
Auditors Allowed:
No
Grading Restriction:
Letter Grade or Pass/Fail
Contact:
Winnie Tang
Course Instructors:
Resources:
Prerequisite:

187.632: Molecular Toxicology or other courses related to molecular biology

Description:

What are the effects of environmental exposures on genome and epigenome? What are the state-of-art ‘omic’ technologies applied for environmental health studies? What is the up-to-date knowledge in genomics and epigenomics? How to reach out the genomic resources, tools, and databases publicly available on the internet?

Presents the concept of the genetic and epigenetic data analysis in environmental health studies. Introduces not only single gene analysis but also genome-wide data searching. Also introduces cutting-edge analytical tools for ‘omic’ data not limited to genomics, but also for epigenomics, proteomics and metabolomics. Provides an introduction to the pathway analysis for ‘omic’ data.

Learning Objectives:

Upon successfully completing this course, students will be able to:

  1. Explain the basic knowledge for genomic and epigenomic data analysis
  2. Identify the difference between omic based network analysis and the traditional lab-based analysis
  3. Describe the approaches used for in silico analysis of the genome
  4. Describe the publicly available tools for the genomic and epigenetic database access and searching
  5. Explain the computational analyses used to identify or validate cellular pathways
Methods of Assessment:

Participation (20%) Attendance and participation in discussion
Quizzes from 4 sessions (80%)

Instructor Consent:

No consent required