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Biological Response to Biomaterials

East Baltimore
4th term
Molecular Microbiology and Immunology
3 credits
Academic Year:
2019 - 2020
Class Times:
  • Tu Th,  3:30 - 4:50pm
Auditors Allowed:
Yes, with instructor consent
Grading Restriction:
Letter Grade or Pass/Fail
Course Instructor :
  • Carmelita Frondoza
Carmelita Frondoza

Focuses on the clinical applications of biomaterials as medical devices: (1) to repair, replace organs and tissues; and (2) to deliver drugs, growth factors and other agents to stimulate, enhance, and restore function. Discusses biomaterials used in clinical settings such as orthopedics, cardiovascular, dental, and reconstructive surgery. Covers chemical, physical and mechanical properties of currently used and new biomaterials. Presents biological responses (immune and non-immune) that determine success or failure of biomaterial devices. Provides state-of the art information on public health concerns with respect to the use of biomaterials in medicine.

Learning Objectives:

Upon successfully completing this course, students will be able to:

  1. Identify biomaterials used for tissue regeneration, repair and replacement and as delivery systems for restoration of function
  2. Explain tissue, organ, system response (non-immune, immune) to biomaterials
  3. Discuss regulatory issues for public health safety with the use of standard and new biomaterial compositions and combination devices
Methods of Assessment:

Student evaluation based on mid-term and final exams.

Instructor Consent:

No consent required