Stem Cells and the Biology of Aging and Disease
- East Baltimore
- 3rd term
- Biochemistry and Molecular Biology
- 3 credits
- Academic Year:
- 2019 - 2020
- Class Times:
- M W, 10:30 - 11:50am
Course in biochemistry, molecular biology, or cell biology at undergraduate or graduate level.
Exposes students to cutting-edge topics in stem cell biology through a combination of lectures and discussions based on primary literature. Topics include basic stem cell biology in a invertebrate and vertebrate systems, including germline, neural, and hematopoietic stem cells; the regulation of stem cells by physiology and aging; the connection between stem cells, telomerase, and cancer; and ethical issues pertaining to potential therapeutic applications of stem cells.
- Learning Objectives:
- Explain some of the basic cellular and molecular mechanisms that ensure self-renewal of stem cells
- Compare and contrast the regulation and function of stem cells in different systems
- Explain how physiology and aging impacts stem cell behavior and function
- Discuss how telomerase function is relevant to stem cells and cancers
- Raise some of the ethical issues in stem cell research and its therapeutic applications.
- Methods of Assessment:
Midterm - 50%; Final - 50%
- Instructor Consent:
No consent required