120.626.01
Principles of Cell Biology
Location
East Baltimore
Term
2nd Term
Department
Biochemistry and Molecular Biology
Credit(s)
3
Academic Year
2019 - 2020
Instruction Method
TBD
W, F, 9:00 - 10:20am
Auditors Allowed
Yes, with instructor consent
Available to Undergraduate
No
Grading Restriction
Letter Grade or Pass/Fail
Course Instructor(s)
Contact Name
Frequency Schedule
Every Year
Resources
Prerequisite
Introductory courses in Genetics and/or Molecular and Cell Biology (such as 120.602). Students should also have a basic understanding of molecular genetics (i.e. the roles of DNA and RNA in protein synthesis) and a basic understanding of protein structure and function.
Provides students with a basic understanding of the structure and functions of eukaryotic cells. Introduces students to new facts and vocabulary pertinent to cell biology, as well as experimental methods used by scientists to define and understand cell structure and functions. Highlights relationships between defects in basic cell functions and human diseases. Classroom time is divided into formal lecture session as well as one less formal discussion/problem solving session.
Learning Objectives
Upon successfully completing this course, students will be able to:
- Identify the intracellular organelles of eukaryotic cells and describe their functions
- Describe the proteins and mechanisms regulating ion and small molecule transport across membranes
- Define the structure and functions of cytoskeleton
- Understand the mechanisms on protein sorting and translocation into sub-cellular organelles
- Describe nuclear structure and function, chromosomal organization, and their relationships to gene expression
- Understand the basic principles of cellular signal transduction
- Define the key events during cell cycle and cell death
- Describe the structure and functions of cell junctions and extracellular matrix
- Understand the stem cell function and the procedure of tissue renewal
- Define the key cell biology events during two pathophysiological conditions, i.e. pathogens and infection, and cancer
Methods of Assessment
This course is evaluated as follows:
- 45% Exam(s)
- 45% Exam(s)
- 10% Participation