120.604.81 Introduction to Molecular Biology
- Biochemistry and Molecular Biology
- 1st term
- 3 credits
- Academic Year:
- 2019 - 2020
Introduction to Online Learning. A strong college level background in the biological sciences is required.
Molecular biology deals with how nucleic acids and proteins interact within the cell to promote proper growth, division, and development. This course will provide an overview of these processes, including DNA replication, repair, transcription, splicing, protein synthesis, and gene regulation in different organisms. We will also explore many biological tools that have been developed from molecular biology processes, such as DNA sequencing and gene editing (CRISPR-Cas9).
- Learning Objectives:
- Compare and contrast bacterial and eukaryotic DNA replication, DNA repair, transcription, and translation
- Give examples of DNA and histone modifications and predict how they will affect gene expression.
- Describe how pre-mRNA splicing occurs and explain how alternative splicing can generate protein diversity.
- Explain how molecular biology processes like the CRISPR-Cas9 system are being used to modify eukaryotic genomes.
- Distinguish between different molecular biology techniques that are used to isolate, separate, and probe for specific nucleic acids, proteins, and their interactions.
- Methods of Assessment:
Grades will be based on three online exams, each 1/3 of the final grade. Exams will be composed of Multiple choice or short answer questions. Students will also participate in 3 live talk sessions (not graded).
The exams will assess the students knowledge and comprehension of the material covered as well as their ability to synthesize and apply this knowledge to new situations.
- Enrollment Restriction:
CANNOT take this course if already enrolled or completed 120.602.01 Concepts of Molecular Biology
- Instructor Consent:
No consent required