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Course Catalog

340.728.01 Advanced Methods for Design and Analysis of Cohort Studies

1st term
5 credits
Academic Year:
2019 - 2020
East Baltimore
Class Times:
  • Tu Th,  8:30 - 10:20am
  • Monday,  8:30 - 9:20am
Auditors Allowed:
Grading Restriction:
Letter Grade or Pass/Fail
Dr. Alvaro Munoz
Course Instructor s:

340.753 and 140.623 or 653. Knowledge of statistical package.


Explores advanced methods useful for the design and analysis of cohort studies. Emphasizes methods for analyzing time-to-event data subject to staggered entries using advanced parametric and semi-parametric methods; analytical methods for incomplete observations in cohort studies; methods to measure effects of exposures on time-to-event using relative times and relative hazards; parametric survival analysis methods and taxonomy of hazard functions; coefficients of determination based on parametric models for survival data; regression methods for trajectories of biomarkers; methods for the analysis of interventions in observational studies: confounding by indication, marginal structural models for individual effectiveness; methods for estimating population effectiveness; and methods to jointly analyze longitudinal and survival data.

Learning Objectives:

Upon successfully completing this course, students will be able to:

  1. Analyze a moderately complicated real life data set from a large, long-term multicenter cohort study using advanced methods discussed in the lectures
  2. Write a scientific report with a “Methods” and a “Results” section of a publishable manuscript
Methods of Assessment:

lab presentations and submission of two completed lab reports (25%); preparation of a final report (75%)

Instructor Consent:

No consent required