260.611.01 Principles of Immunology I
- Molecular Microbiology and Immunology
- 1st term
- 4 credits
- Academic Year:
- 2019 - 2020
- East Baltimore
- Class Times:
- Tu Th, 8:30 - 10:20am
A course in advanced biology
Introduces biological concepts of immunology; molecular nature of antigens; molecular basis for antibody and T-cell receptor structure and diversity; complement; hypersensitivity reactions; cellular basis for the immune response; cell-mediated immunity; adhesion molecules and coreceptors cell activation; cytokines and other soluble mediators; major histocompatibility complex (MHC) antigens; tumor immunology; transplantation immunobiology; mechanisms of resistance to microorganisms; tolerance; autoimmunity; and immuno-deficiency.
- Learning Objectives:
- Define the tissue, cellular and molecular components that constitute the vertebrate innate and adaptive immune system
- Explain the generation of lymphocyte antigen receptors and the molecular and cellular basis for diversity and specificity of receptors on immune cells
- Define the basis for antigen presentation to T cells
- Define the basis for recognition of self and non-self recognition
- Define the development and survival of lymphocytes
- Explain the major signaling pathways used by immune cells
- Define T cell-mediated and B cell-mediated immunity
- Methods of Assessment:
Student evaluation based on mid-term and final exams.
- Instructor Consent:
Consent required for some students
- Consent Note:
Consent is required for undergraduate students.
- For consent, contact:
- Special Comments:
Required for MMI PhD students.