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120.624.01
Cancer Biology

Location
East Baltimore
Term
4th Term
Department
Biochemistry and Molecular Biology
Credit(s)
3
Academic Year
2018 - 2019
Instruction Method
TBD
Class Time(s)
M, W, 3:30 - 4:50pm
Auditors Allowed
Yes, with instructor consent
Available to Undergraduate
No
Grading Restriction
Letter Grade or Pass/Fail
Course Instructor(s)
Contact Name
Frequency Schedule
Every Year
Description
Presents the molecular and cellular mechanisms in the biology of cancer. Topics include Oncogenes and tumor suppressor genes, DNA damage responses, p53 signaling pathway, NF-kB signaling pathway, chemotherapy and radiotherapy, and several key research fields in major select human cancers. Emphasizes the relevance of these mechanisms to the development and treatment of human cancer.
Learning Objectives
Upon successfully completing this course, students will be able to:
  1. Understand the key hallmarks associated with cancer development
  2. Understand how exposure to various environmental agents could lead to carcinogenesis in normal cells and how chemotherapy- and radiotherapy-based anti-cancer drugs can kill cancer cells
  3. Define the cellular signaling cascade in response to environmental and intrinsic DNA damage in normal and cancer cells
  4. Define the importance of several key signaling pathways in the cellular response to DNA damage
  5. Understand the mechanisms by which the cell determines the fate for survival and death
  6. Understand the current research in major select human cancers
Enrollment Restriction
Undergraduates prohibited from enrolling in this course.