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330.690.11
Applications and Analysis of Epigenetic Data in Public Health Research

Course Status
Cancelled

Location
East Baltimore
Term
Summer Institute
Department
Mental Health
Credit(s)
1
Academic Year
2018 - 2019
Instruction Method
TBD
Start Date
Monday, June 4, 2018
End Date
Monday, June 4, 2018
Class Time(s)
Monday, 8:30am - 5:00pm
Auditors Allowed
No
Available to Undergraduate
No
Grading Restriction
Pass/Fail
Contact Name
Frequency Schedule
One Year Only
Description
This course will describe the rationale for inclusion of epigenetic measurement in public health research. It will then describe molecular measurement options, design choices, and analytic approaches to such data in the study of environmental and genetic epidemiology.
Presents applications of epigenetic measurement in public health research. Begins by providing a rationale for such work, then describing measurement tools, from single-site methylation typing, to array-based methods, and whole-genome sequencing. Study design options, quality control analyses, and association analyses will then be presented. Examples based on both mental and physical health outcomes will be used.
Learning Objectives
Upon successfully completing this course, students will be able to:
  1. Describe the rationale for including epigenetic measurements in public health research
  2. Describe the single-site and genome-scale approaches to epigenetic measurement, appropriate for public health research
  3. Apply quality-control analysis to epigenetic data generated in epidemiologic sample sets
  4. Apply association analyses to identify epigenetic marks associated with genes, exposures, and/or disease outcomes
Special Comments

This one-day course is offered in partnership with the Department of Epidemiology course 340.833.11 DESIGNS AND ANALYSIS FOR HUMAN GENOMIC SEQUENCING DATA. Participants are encouraged to register for both courses. An optional second day epigenetic computing laboratory (330.990.11) will be offered to teach the software implementation of methods described in the course.